Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INP99_RS06110 Genome accession   NZ_CP063111
Coordinates   1238811..1240637 (+) Length   608 a.a.
NCBI ID   WP_111315514.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C152_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1233811..1245637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP99_RS06085 (INP99_06075) msbA 1233821..1235584 (+) 1764 WP_197541864.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INP99_RS06090 (INP99_06080) lpxK 1235638..1236618 (+) 981 WP_065244352.1 tetraacyldisaccharide 4'-kinase -
  INP99_RS06095 (INP99_06085) - 1236636..1236815 (+) 180 WP_005696424.1 Trm112 family protein -
  INP99_RS06100 (INP99_06090) kdsB 1236825..1237589 (+) 765 WP_197541865.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INP99_RS06105 (INP99_06095) - 1237764..1238717 (+) 954 WP_197541866.1 hypothetical protein -
  INP99_RS06110 (INP99_06100) uvrC 1238811..1240637 (+) 1827 WP_111315514.1 excinuclease ABC subunit UvrC Machinery gene
  INP99_RS06115 (INP99_06105) - 1240706..1241425 (+) 720 WP_111315515.1 TerC family protein -
  INP99_RS06120 (INP99_06110) - 1241464..1242516 (-) 1053 WP_049370160.1 ABC transporter ATP-binding protein -
  INP99_RS06125 (INP99_06115) - 1242530..1244050 (-) 1521 WP_049370161.1 ABC transporter permease -
  INP99_RS06130 (INP99_06120) - 1244135..1245133 (-) 999 WP_049355936.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69194.06 Da        Isoelectric Point: 9.0442

>NTDB_id=436396 INP99_RS06110 WP_111315514.1 1238811..1240637(+) (uvrC) [Haemophilus parainfluenzae strain M1C152_1]
MFDSKKFLSDVSHKPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINVKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436396 INP99_RS06110 WP_111315514.1 1238811..1240637(+) (uvrC) [Haemophilus parainfluenzae strain M1C152_1]
ATGTTCGATTCTAAAAAGTTTCTCTCTGACGTTTCTCATAAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTAAAAAAGCGCCTTTCCAGCTACTTCCGAAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATTGATACGACGATTACTTCTTCAGAAACTGAAGCGCTATTGCTAGAGCACAAC
TTCATTAAGCTTTATCAACCTCGTTATAATGTGTTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGCGGAACGAAAAAAATAGCAGGCGAGTATTTCGGGCCTTATCCTCATGCGGGGG
CAGTACGTGAAACCTTGTCGTTAATGCAAAAACTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATTGGGCGTTGCTCCGCACCTTGTGTGCCAGGCTATGTGACTGATGAGGAATATAACCA
ACAAGTCGAATTAGCACGACTATTTTTACAAGGAAAAGATCAGCAAGTATTAGATTATCTCATTGGAAAAATGGAGCAGG
CGAGCCGAGACTTAGATTTTGAAGGTGCGGCGCGTTATCGTGACCAAATTCAAGCGGTTCGTGCTGTTATCGAAAAACAA
TTTGTTTCCAATGAGCGTTTGGACGATATGGATATTATGTCCATTGCGTATCAGCACGGTTTAGCTTGTGTTCAGGTAAT
GTTTATTCGTCAAGGTAAAGTATTAGGTAATCGCAGTTATTTTCCGAAAGTGCCTGCTAATACTGATTTATCTGAACTCA
CAGCCACTTTTGTTGGGCAGTTCTATTTGCAAGGTCATCAGGGAAGAAGTATCCCAAATAGTATTATTGTGGATCATAAA
TTAGATGAAAAAGCGGAGCTTGAGGCCTTATTAACTGAACAAGCTGGCCGAAAAGTGGTGATACAAGAATCTGCTAAAGG
CGATAAAGGTAAATATCTACAACTAGCACAAATTAATGTCAAAGCGGCTTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGCACGAACGTTATCAAGCCCTTTGTGAGTTACTCGATATGCCTGAAATTAAACGCATGGAATGTTTTGATATTAGCCAT
ACGATGGGTAATCAAACTGTGGCATCTTGCGTAGTCTTTAACCAAGAAGGCCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGCATTACTGGCGGCGATGATTATGCAGCGATGGAGCAAGCCTTAAAGAAACGTTATGACCGCGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCATCTC
AACGTGAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGAGTCGATCGTCGAGCAGGACAAGAAGTGTT
GATTATCAGCAAACAAGATCGTGAAATCCATTTGCCAGATGATAGTCTTGCGCTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGTGGTCACCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGATTGGAAACCATTGAA
GGGGTAGGCGCTAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTGCAAGGTGTCAAAAATGCCACGTTGGATGA
AATCGCCTCTGTACCTGGTATTTCTAAAGCGTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-235)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.793

98.355

0.372
  uvrC Streptococcus pneumoniae R6

37.458

98.355

0.368
  uvrC Streptococcus pneumoniae D39

37.458

98.355

0.368