Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   INQ00_RS06135 Genome accession   NZ_CP063110
Coordinates   1238907..1240733 (+) Length   608 a.a.
NCBI ID   WP_049365378.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C160_1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1233907..1245733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INQ00_RS06115 (INQ00_06120) msbA 1235150..1236898 (+) 1749 WP_197546509.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  INQ00_RS06120 (INQ00_06125) lpxK 1236952..1237932 (+) 981 WP_197546510.1 tetraacyldisaccharide 4'-kinase -
  INQ00_RS06125 (INQ00_06130) - 1237950..1238129 (+) 180 WP_111326848.1 Trm112 family protein -
  INQ00_RS06130 (INQ00_06135) kdsB 1238139..1238897 (+) 759 WP_197546511.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  INQ00_RS06135 (INQ00_06140) uvrC 1238907..1240733 (+) 1827 WP_049365378.1 excinuclease ABC subunit UvrC Machinery gene
  INQ00_RS06140 (INQ00_06145) - 1240803..1241522 (+) 720 WP_049365379.1 TerC family protein -
  INQ00_RS06145 (INQ00_06150) - 1241561..1242613 (-) 1053 WP_049370160.1 ABC transporter ATP-binding protein -
  INQ00_RS06150 (INQ00_06155) - 1242627..1244147 (-) 1521 WP_049370161.1 ABC transporter permease -
  INQ00_RS06155 (INQ00_06160) - 1244240..1245238 (-) 999 WP_111326855.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69220.01 Da        Isoelectric Point: 8.8121

>NTDB_id=436335 INQ00_RS06135 WP_049365378.1 1238907..1240733(+) (uvrC) [Haemophilus parainfluenzae strain M1C160_1]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKIAGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCSAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKAELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMYERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAINGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=436335 INQ00_RS06135 WP_049365378.1 1238907..1240733(+) (uvrC) [Haemophilus parainfluenzae strain M1C160_1]
ATGTTTGATTCTAAAAAGTTTCTCTCTGACGTTTCTCATGAGCCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTAGGCAAAGCGAAAGATCTTAAAAAGCGACTTTCCAGCTATTTTCGCAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATTGATACGACGATTACCTCTTCTGAAACCGAAGCGTTATTGCTTGAGCATAAT
TTCATTAAGCTTTATCAACCTCGTTATAATGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTACTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGCGGAACGAAAAAAATTGCAGGTGAGTATTTCGGGCCTTATCCTCATGCGGGGG
CTGTGCGTGAAACCTTATCCTTAATGCAAAAACTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGCTCAGCACCTTGTGTGCCAGGCTATGTGACTGATGAAGAATATAATCA
GCAAGTCGAATTAGCACGACTATTTTTACAAGGAAAAGATCAGCAAGTATTAGATTATCTCATCGGCAAAATGGAGCAGG
CGAGCCGTGATTTAGATTTTGAAGGTGCGGCACGTTATCGTGACCAAATTCAAGCGGTTCGTGCGGTTATCGAAAAACAA
TTTGTTTCCAATGAGCGTTTGGACGATATGGATATTATGTCCATTGCGTATCAGCACGGTTTAGCTTGTGTTCAAGTGAT
GTTTATTCGTCAAGGTAAAGTATTGGGCAATCGCAGTTATTTTCCGAAAGTACCTGCTAATACTGATTTGTCCGAATTAA
CGGCGACGTTTGTTGGGCAGTTTTATTTGCAAGGTCATCAGGGAAGAAGTATCCCTAATAGTATTATTGTGGATCATAAA
CTAGATGAAAAAGCCGAGCTTGAAGCTTTATTAACTGAACAAGCTGGTCGAAAAGTGGTAATACAAGAATCTGCTAAAGG
CGATAAAGGTAAATATCTACAACTTGCACAAATTAATGCCAAAGCGGCTTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGTACGAACGTTATCAAGCGCTTTGTGAATTGCTCGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGTCAT
ACGATGGGGAATCAAACCGTGGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGCCGTTTTAA
TATTGAAGGTATTACGGGTGGTGATGATTATGCAGCGATGGAGCAAGCTTTAAAGAAACGTTACGACCGCGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGGCAGCTTAATCGTGCCTTAGAGGTTTTTCATCACCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATTGGTGTGGCAAAAGGTGTAGATCGTCGAGCGGGACAAGAAGTGTT
GATTATCAGCAAACAAGATCGTGAGATTCATTTGCCGGATGATAGCCTTGCACTACATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAACGGTCATCGTCAAAAACGCCAAAAAGCCTTTACCCAAAGTGGATTGGAAACTATTGAA
GGGGTAGGCGCTAAACGACGTCAAGCCTTGTTGAAATATTTAGGTGGATTGCAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCTGTACCCGGTATTTCTAAAGCCTTAGCCGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

Helix-hairpin-helix domain (HHH_5)

(556-607)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.96

98.355

0.373
  uvrC Streptococcus pneumoniae R6

37.625

98.355

0.37
  uvrC Streptococcus pneumoniae D39

37.625

98.355

0.37