Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SMUGS5_RS09470 Genome accession   NC_018089
Coordinates   1954254..1956209 (-) Length   651 a.a.
NCBI ID   WP_002280521.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1949254..1961209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS09445 (SMUGS5_09385) spx 1949752..1950150 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUGS5_RS09450 (SMUGS5_09390) recA 1950235..1951386 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUGS5_RS09455 (SMUGS5_09395) cinA 1951426..1952682 (-) 1257 WP_002270966.1 competence/damage-inducible protein A Machinery gene
  SMUGS5_RS09460 (SMUGS5_09400) - 1952831..1953391 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  SMUGS5_RS09465 (SMUGS5_09405) ruvA 1953473..1954066 (-) 594 WP_014835067.1 Holliday junction branch migration protein RuvA Machinery gene
  SMUGS5_RS09470 (SMUGS5_09410) hexB 1954254..1956209 (-) 1956 WP_002280521.1 DNA mismatch repair endonuclease MutL Machinery gene
  SMUGS5_RS10270 - 1956434..1956712 (+) 279 Protein_1844 transposase -
  SMUGS5_RS09480 (SMUGS5_09420) hexA 1956707..1959256 (-) 2550 WP_002275705.1 DNA mismatch repair protein MutS Machinery gene
  SMUGS5_RS09485 (SMUGS5_09425) - 1959249..1959596 (-) 348 WP_002274702.1 YlbF family regulator -
  SMUGS5_RS09490 (SMUGS5_09430) argR 1959593..1960030 (-) 438 WP_002262400.1 arginine repressor -
  SMUGS5_RS09495 (SMUGS5_09435) - 1960427..1960939 (-) 513 WP_014835068.1 Crp/Fnr family transcriptional regulator -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73786.47 Da        Isoelectric Point: 6.4076

>NTDB_id=43583 SMUGS5_RS09470 WP_002280521.1 1954254..1956209(-) (hexB) [Streptococcus mutans GS-5]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVIDNGQGIEQADVIMSLRRHATSK
IKKQSDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIHGTLVIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLYYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLTMTDKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGVHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=43583 SMUGS5_RS09470 WP_002280521.1 1954254..1956209(-) (hexB) [Streptococcus mutans GS-5]
ATGTCAAAAATTATTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGATTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGCCATGCAACTAGTAAG
ATTAAAAAACAATCCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATACATGGCACTTTAGTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTTATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCAGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACCCGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGTGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTACT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGTATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAACTTCCTCTTAAACAATCAAATCTTTACTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTACTATGACAGATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATTATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTTGGAGTTCACTTAGAAAACT
ATGGAGAGAATACTTTTATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAATTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGGGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(453-595)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-135)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.909

100

0.707

Multiple sequence alignment