Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IMP05_RS01405 Genome accession   NZ_CP062910
Coordinates   249671..250327 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O112ab:H8 strain Res13-Lact-EA06-22     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 244671..255327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMP05_RS01375 (IMP05_01375) dcyD 245551..246537 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IMP05_RS01380 (IMP05_01380) tcyL 246552..247220 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IMP05_RS01385 (IMP05_01385) tcyN 247217..247969 (+) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IMP05_RS01390 (IMP05_01390) sdiA 248199..248921 (+) 723 WP_001154285.1 transcriptional regulator SdiA -
  IMP05_RS01395 (IMP05_01395) yecF 248988..249212 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IMP05_RS01400 (IMP05_01400) yecU 249199..249375 (-) 177 WP_000590347.1 protein YecU -
  IMP05_RS01405 (IMP05_01405) letA 249671..250327 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IMP05_RS01410 (IMP05_01410) uvrC 250324..252156 (+) 1833 WP_033801059.1 excinuclease ABC subunit UvrC Machinery gene
  IMP05_RS01415 (IMP05_01415) pgsA 252213..252761 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IMP05_RS01435 (IMP05_01435) yecA 253410..254075 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=435718 IMP05_RS01405 WP_000611335.1 249671..250327(+) (letA) [Escherichia coli O112ab:H8 strain Res13-Lact-EA06-22]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=435718 IMP05_RS01405 WP_000611335.1 249671..250327(+) (letA) [Escherichia coli O112ab:H8 strain Res13-Lact-EA06-22]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486