Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SMUGS5_RS05585 Genome accession   NC_018089
Coordinates   1162236..1164017 (-) Length   593 a.a.
NCBI ID   WP_002279733.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1157236..1169017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS05570 (SMUGS5_05520) pepV 1157311..1158723 (-) 1413 WP_002279729.1 dipeptidase PepV -
  SMUGS5_RS05575 (SMUGS5_05525) - 1158738..1159340 (-) 603 WP_002264093.1 nitroreductase family protein -
  SMUGS5_RS05580 (SMUGS5_05530) - 1159819..1161423 (-) 1605 WP_002279730.1 AbiH family protein -
  SMUGS5_RS05585 (SMUGS5_05535) uvrC 1162236..1164017 (-) 1782 WP_002279733.1 excinuclease ABC subunit UvrC Machinery gene
  SMUGS5_RS05595 (SMUGS5_05540) - 1164135..1165289 (+) 1155 WP_014834988.1 low temperature requirement protein A -
  SMUGS5_RS05600 (SMUGS5_05545) - 1165333..1166028 (-) 696 WP_002265580.1 YjjG family noncanonical pyrimidine nucleotidase -
  SMUGS5_RS05605 (SMUGS5_05550) - 1166242..1166538 (-) 297 WP_002263197.1 TetR/AcrR family transcriptional regulator -
  SMUGS5_RS05610 (SMUGS5_05555) eno 1166602..1167900 (-) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  SMUGS5_RS05615 (SMUGS5_05560) - 1168295..1168936 (-) 642 WP_002263195.1 DUF4352 domain-containing protein -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68549.04 Da        Isoelectric Point: 9.5116

>NTDB_id=43535 SMUGS5_RS05585 WP_002279733.1 1162236..1164017(-) (uvrC) [Streptococcus mutans GS-5]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSDTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTVCQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRNIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLDGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAEAVKVKLGEEKR

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=43535 SMUGS5_RS05585 WP_002279733.1 1162236..1164017(-) (uvrC) [Streptococcus mutans GS-5]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGTAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTGGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAGATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCGTTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGTTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAAATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGTTGGACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCGGAGGCGGTTAAAGTCAA
GTTGGGGGAGGAGAAAAGATGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

77.381

99.157

0.767
  uvrC Streptococcus pneumoniae R6

77.041

99.157

0.764
  uvrC Streptococcus pneumoniae D39

77.041

99.157

0.764

Multiple sequence alignment