Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IMP69_RS01095 Genome accession   NZ_CP062876
Coordinates   215254..215910 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O157:H16 strain Res13-Lact-PEA12-26     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 210254..220910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMP69_RS01065 (IMP69_01065) dcyD 211134..212120 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  IMP69_RS01070 (IMP69_01070) tcyL 212135..212803 (+) 669 WP_001158213.1 cystine ABC transporter permease -
  IMP69_RS01075 (IMP69_01075) tcyN 212800..213552 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IMP69_RS01080 (IMP69_01080) sdiA 213782..214504 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  IMP69_RS01085 (IMP69_01085) yecF 214571..214795 (-) 225 WP_000106477.1 DUF2594 family protein YecF -
  IMP69_RS01090 (IMP69_01090) yecU 214782..214958 (-) 177 WP_000590347.1 protein YecU -
  IMP69_RS26150 - 215041..215112 (-) 72 Protein_215 transcriptional regulator -
  IMP69_RS01095 (IMP69_01095) letA 215254..215910 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IMP69_RS01100 (IMP69_01100) uvrC 215907..217739 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IMP69_RS01105 (IMP69_01105) pgsA 217796..218344 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IMP69_RS01125 (IMP69_01125) - 219040..219780 (-) 741 WP_000413226.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=435238 IMP69_RS01095 WP_000611335.1 215254..215910(+) (letA) [Escherichia coli O157:H16 strain Res13-Lact-PEA12-26]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=435238 IMP69_RS01095 WP_000611335.1 215254..215910(+) (letA) [Escherichia coli O157:H16 strain Res13-Lact-PEA12-26]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486