Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IMQ20_RS09390 Genome accession   NZ_CP062838
Coordinates   1963151..1963807 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Res13-Lact-PER02-33     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1958151..1968807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMQ20_RS09360 (IMQ20_09370) dcyD 1959030..1960016 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IMQ20_RS09365 (IMQ20_09375) tcyL 1960031..1960699 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IMQ20_RS09370 (IMQ20_09380) tcyN 1960696..1961448 (+) 753 WP_100003997.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IMQ20_RS09375 (IMQ20_09385) sdiA 1961678..1962400 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  IMQ20_RS09380 (IMQ20_09390) yecF 1962468..1962692 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IMQ20_RS09385 (IMQ20_09395) yecU 1962679..1962855 (-) 177 WP_000590344.1 protein YecU -
  IMQ20_RS25470 - 1962893..1963009 (-) 117 Protein_1858 transcriptional regulator -
  IMQ20_RS09390 (IMQ20_09400) letA 1963151..1963807 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IMQ20_RS09395 (IMQ20_09405) uvrC 1963804..1965636 (+) 1833 WP_195686572.1 excinuclease ABC subunit UvrC Machinery gene
  IMQ20_RS09400 (IMQ20_09410) pgsA 1965693..1966241 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IMQ20_RS09420 (IMQ20_09430) yecA 1966891..1967556 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=434640 IMQ20_RS09390 WP_000611335.1 1963151..1963807(+) (letA) [Escherichia coli strain Res13-Lact-PER02-33]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=434640 IMQ20_RS09390 WP_000611335.1 1963151..1963807(+) (letA) [Escherichia coli strain Res13-Lact-PER02-33]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486