Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   HCU70_RS03245 Genome accession   NZ_CP050690
Coordinates   664237..664806 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain PMB179-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 659237..669806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCU70_RS03205 (HCU70_03205) - 659711..660319 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  HCU70_RS03210 (HCU70_03210) rplL 660494..660862 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  HCU70_RS03215 (HCU70_03215) rplJ 660905..661405 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  HCU70_RS03220 (HCU70_03220) rplA 661677..662369 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  HCU70_RS03225 (HCU70_03225) rplK 662577..662999 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  HCU70_RS03230 (HCU70_03230) nusG 663180..663728 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  HCU70_RS03235 (HCU70_03235) secE 663741..663923 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  HCU70_RS03240 (HCU70_03240) rpmG 663979..664122 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  HCU70_RS03245 (HCU70_03245) sigH 664237..664806 (-) 570 WP_000872873.1 RNA polymerase sigma factor Regulator
  HCU70_RS03250 (HCU70_03250) - 664887..665411 (-) 525 WP_000664738.1 NYN domain-containing protein -
  HCU70_RS03255 (HCU70_03255) rlmB 665411..666157 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  HCU70_RS03260 (HCU70_03260) - 666165..666569 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  HCU70_RS03265 (HCU70_03265) cysS 666562..667962 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  HCU70_RS03270 (HCU70_03270) cysE 667946..668593 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=433936 HCU70_RS03245 WP_000872873.1 664237..664806(-) (sigH) [Staphylococcus aureus strain PMB179-1]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=433936 HCU70_RS03245 WP_000872873.1 664237..664806(-) (sigH) [Staphylococcus aureus strain PMB179-1]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984