Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SCIM_RS10055 Genome accession   NC_018073
Coordinates   563617..564438 (-) Length   273 a.a.
NCBI ID   WP_231840239.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 558617..569438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS02800 (SCIM_0494) - 558911..559285 (-) 375 WP_003073369.1 hypothetical protein -
  SCIM_RS02805 (SCIM_0495) comA/nlmT 559766..561916 (+) 2151 WP_004234001.1 peptide cleavage/export ABC transporter Regulator
  SCIM_RS02810 (SCIM_0496) - 561927..563288 (+) 1362 WP_003078103.1 bacteriocin secretion accessory protein -
  SCIM_RS02815 - 563402..563536 (+) 135 WP_004233948.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SCIM_RS10055 comD/blpH 563617..564438 (-) 822 WP_231840239.1 sensor histidine kinase Regulator
  SCIM_RS02825 (SCIM_0498) comE/blpR 564935..565681 (-) 747 WP_037589556.1 response regulator transcription factor Regulator
  SCIM_RS02830 (SCIM_0499) - 565850..566563 (-) 714 WP_004233848.1 CPBP family intramembrane glutamic endopeptidase -
  SCIM_RS02835 - 566795..567022 (+) 228 WP_004233901.1 bacteriocin -
  SCIM_RS02840 (SCIM_0500) - 567058..567378 (+) 321 WP_003073339.1 hypothetical protein -
  SCIM_RS02845 - 567608..567823 (+) 216 WP_004233876.1 bacteriocin class II family protein -
  SCIM_RS02850 (SCIM_0501) - 568051..568344 (+) 294 WP_004233800.1 bacteriocin immunity protein -
  SCIM_RS02855 - 568438..568662 (+) 225 WP_004234003.1 Blp family class II bacteriocin -
  SCIM_RS09905 - 569078..569224 (+) 147 WP_004233732.1 hypothetical protein -

Sequence

Protein


Download         Length: 273 a.a.        Molecular weight: 31185.02 Da        Isoelectric Point: 6.4236

>NTDB_id=43377 SCIM_RS10055 WP_231840239.1 563617..564438(-) (comD/blpH) [Streptococcus intermedius JTH08]
MVLYYIILQLLAYIEYTKFTTTLFVREALVIIYLVFFLIITNRLDLHLRERIQNDLMLQKDLQLKNLENYSHHIEELYTE
VRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAAKFAQAQEHNVSVSL
EVPEDICPQGMELVDFITIVSILCDNAIEAAAPTMTIAYVLSGNKQVFSIENAIKEEHIDMSYIFDAGVSSKGSGRGIGL
SNVLAILDRYPNVSLASTSQNHCFQHILEIHLN

Nucleotide


Download         Length: 822 bp        

>NTDB_id=43377 SCIM_RS10055 WP_231840239.1 563617..564438(-) (comD/blpH) [Streptococcus intermedius JTH08]
ATGGTATTGTACTATATCATTCTCCAACTATTGGCGTATATAGAATACACTAAATTTACAACAACTCTTTTTGTTAGAGA
AGCATTGGTTATTATTTATCTAGTATTCTTTTTGATTATTACTAACCGACTGGACCTTCATTTACGGGAGAGAATCCAAA
ATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAACTTGGAAAACTACAGTCATCACATTGAAGAATTGTACACAGAA
GTTCGGAGCTTTCGGCATGATTACGCAAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATATAGGCATTGT
AAAGAATGTTTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGACGGTTAGTCC
ATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATCCGTTTCATTG
GAAGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGTGTGATAATGC
GATTGAAGCTGCTGCTCCAACTATGACGATTGCTTATGTTTTGTCAGGAAACAAGCAGGTATTCTCCATTGAAAATGCTA
TAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGGAATTGGATTA
TCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCACTTGCTAGTACTAGCCAGAATCACTGCTTTCAGCACAT
CCTTGAGATTCATCTGAATTAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(171-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

44.526

100

0.447
  comD/comD3 Streptococcus equinus JB1

39.442

91.941

0.363

Multiple sequence alignment