Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   SCIM_RS09775 Genome accession   NC_018073
Coordinates   1930267..1930413 (-) Length   48 a.a.
NCBI ID   WP_003075491.1    Uniprot ID   O33651
Organism   Streptococcus intermedius JTH08     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1925267..1935413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS09455 (SCIM_1702) - 1925276..1927852 (+) 2577 WP_003077344.1 YfhO family protein -
  SCIM_RS09470 (SCIM_1703) comE 1928176..1928925 (-) 750 WP_003075577.1 competence system response regulator transcription factor ComE Regulator
  SCIM_RS09475 (SCIM_1704) comD/comD1 1928925..1930250 (-) 1326 WP_014829844.1 GHKL domain-containing protein Regulator
  SCIM_RS09775 comC 1930267..1930413 (-) 147 WP_003075491.1 bacteriocin Regulator
  SCIM_RS09490 (SCIM_1705) rlmH 1930690..1931169 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SCIM_RS09495 (SCIM_1706) htrA 1931373..1932563 (+) 1191 WP_003075586.1 S1C family serine protease Regulator
  SCIM_RS09500 (SCIM_1707) spo0J 1932618..1933385 (+) 768 WP_003075591.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 48 a.a.        Molecular weight: 5605.69 Da        Isoelectric Point: 10.5532

>NTDB_id=43376 SCIM_RS09775 WP_003075491.1 1930267..1930413(-) (comC) [Streptococcus intermedius JTH08]
MKKLFAKKEVVKKEVVKFKELNDEQLDKVIGGDSRIRMGFDFSKLFGK

Nucleotide


Download         Length: 147 bp        

>NTDB_id=43376 SCIM_RS09775 WP_003075491.1 1930267..1930413(-) (comC) [Streptococcus intermedius JTH08]
ATGAAAAAGTTGTTTGCTAAAAAAGAGGTAGTAAAAAAGGAAGTTGTGAAATTTAAAGAGTTAAATGATGAACAGTTAGA
TAAAGTTATTGGTGGGGATAGTCGAATCAGAATGGGATTTGATTTTTCTAAACTTTTTGGTAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O33651

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

54.054

77.083

0.417

Multiple sequence alignment