Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HCN55_RS06295 Genome accession   NZ_CP050532
Coordinates   1222351..1223007 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis subsp. subtilis str. SMY     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217351..1228007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCN55_RS06265 (HCN55_06270) oppF 1217816..1218733 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HCN55_RS06270 (HCN55_06275) yjbB 1218840..1220057 (+) 1218 WP_010886478.1 MFS transporter -
  HCN55_RS06275 (HCN55_06280) yjbC 1220221..1220799 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  HCN55_RS06280 (HCN55_06285) spx 1220980..1221375 (+) 396 WP_003245483.1 transcriptional regulator Spx -
  HCN55_RS06285 (HCN55_06290) yjbE 1221418..1222074 (-) 657 WP_003232944.1 TerC family protein -
  HCN55_RS06290 (HCN55_06295) - 1222244..1222384 (+) 141 WP_119122854.1 hypothetical protein -
  HCN55_RS06295 (HCN55_06300) mecA 1222351..1223007 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  HCN55_RS06300 (HCN55_06305) - 1223002..1223124 (-) 123 WP_003245684.1 hypothetical protein -
  HCN55_RS06305 (HCN55_06310) coiA 1223198..1224319 (+) 1122 WP_010886479.1 competence protein CoiA Machinery gene
  HCN55_RS06310 (HCN55_06315) pepF 1224549..1226378 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  HCN55_RS06315 (HCN55_06320) - 1226416..1226583 (-) 168 WP_003244944.1 hypothetical protein -
  HCN55_RS06320 (HCN55_06325) spxH 1226897..1227796 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=433729 HCN55_RS06295 WP_003245194.1 1222351..1223007(+) (mecA) [Bacillus subtilis subsp. subtilis str. SMY]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=433729 HCN55_RS06295 WP_003245194.1 1222351..1223007(+) (mecA) [Bacillus subtilis subsp. subtilis str. SMY]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1