Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SCIM_RS03335 Genome accession   NC_018073
Coordinates   686963..688771 (+) Length   602 a.a.
NCBI ID   WP_004233915.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 681963..693771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS03320 nrdH 684019..684237 (-) 219 WP_003073148.1 glutaredoxin-like protein NrdH -
  SCIM_RS03325 - 684619..684882 (+) 264 WP_003068444.1 phosphocarrier protein HPr -
  SCIM_RS03330 (SCIM_0590) ptsP 684884..686617 (+) 1734 WP_004233783.1 phosphoenolpyruvate--protein phosphotransferase -
  SCIM_RS03335 (SCIM_0591) uvrC 686963..688771 (+) 1809 WP_004233915.1 excinuclease ABC subunit UvrC Machinery gene
  SCIM_RS03340 (SCIM_0592) - 688878..689483 (+) 606 WP_003073142.1 nitroreductase family protein -
  SCIM_RS03345 (SCIM_0593) pepV 689501..690901 (+) 1401 WP_003073138.1 dipeptidase PepV -
  SCIM_RS03350 (SCIM_0594) - 691668..692252 (+) 585 WP_004233759.1 uracil-DNA glycosylase family protein -
  SCIM_RS03355 (SCIM_0595) - 692355..692807 (+) 453 WP_004233842.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69284.84 Da        Isoelectric Point: 9.3243

>NTDB_id=43302 SCIM_RS03335 WP_004233915.1 686963..688771(+) (uvrC) [Streptococcus intermedius JTH08]
MNNLIKSKLELLPTGPGCYIHKNKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEVEDFEFIVTESNIEALLLEIN
LIKENQPKYNIMLKDDKSYPFIKITNETYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTICHNAPHFFQEMAQEVADFLKGHDNKIIDELKEKMTSAAEKMEFEKAAEYRDLLQSIATLRTKQRVMAR
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQNTSHLVPNEILIPSDIDEESVRAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGRLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNVAKDVIQHQLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMKHFKSL
TKIKEASVEEIVEVGVPRKVAEAVQGKLRRAIDKKEIIPDTF

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=43302 SCIM_RS03335 WP_004233915.1 686963..688771(+) (uvrC) [Streptococcus intermedius JTH08]
ATGAACAACTTAATTAAATCAAAATTAGAGTTATTGCCAACTGGTCCAGGATGTTATATCCACAAGAATAAAAATGGTAC
GATCATCTATGTGGGAAAAGCCAAGAATTTGCGCAATCGGGTGCGTTCGTATTTTCGCGGAAGTCATGATACTAAAACGG
AAGCGTTAGTGTCTGAGGTTGAGGATTTTGAGTTTATTGTCACTGAGTCTAATATTGAAGCTTTGTTGCTTGAAATCAAT
CTTATCAAGGAAAATCAACCCAAATATAACATCATGCTTAAGGACGATAAGTCCTATCCTTTTATCAAAATTACCAATGA
GACATATCCGCGGCTTATAATCACACGTCAGGTTAAGAAAGATGGTGGTTTATATTTTGGCCCGTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCCTACTGGATCGCATTTTCCCTTTCCGAAAGTGTACTAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTATCTGCCATAATGCCCCACATTTCTTTCAAGAGATGGCTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGAAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAATACCGAGATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATGGCAAGG
GATTTACAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTTTGACCTATATTGGACAAT
TTTATCAGAATACATCTCATCTGGTGCCCAATGAAATTTTGATTCCATCTGATATTGACGAGGAATCAGTACGGGCTGTG
GTGGATACAAAAATTCTCAAGCCTCAACGAGGAGAAAAGAAACAGCTGGTCAATTTGGCAATTAAGAATGCTCAAGTTAG
TTTACAACAGAAGTTTGACTTATTAGAGAAATCTGTTGAAAAAACGCAAGGAGCAATTGAAAATCTAGGCCGGCTCCTCA
ATATTCCCACTCCAGTTCGGATTGAGTCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATTAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCGGATGACTATGCCAG
TATGCGGGAAGTCATCAAGCGTCGCTACAGCCGAGTTATGCGAGATGGTTTAATACCGCCTGATCTGATTGTCATTGATG
GTGGTCAGGGCCAAGTCAACGTTGCTAAAGACGTCATTCAACATCAATTAGGTTTAGATATTCCTATCGCTGGTTTGCAA
AAGAACGACAAGCATCAGACTCATGAATTGCTTTTTGGTGATCCATTGGAAGTGGTCGAATTATCTCGTAATTCCCAGGA
ATTTTTCCTTTTGCAACGCATCCAAGATGAAGTCCACCGTTTTGCCATTACCTTCCATCGCCAGCTCCGGTCTAAGAATT
CCTTCTCATCACAACTAGATGGCATTGAAGGTTTGGGACCAAAACGCAAGCAAAATCTCATGAAGCATTTCAAATCGCTA
ACCAAGATTAAAGAAGCAAGTGTTGAGGAAATTGTCGAAGTAGGCGTACCGCGAAAAGTAGCAGAGGCTGTTCAGGGGAA
GTTAAGAAGGGCTATAGATAAAAAAGAAATAATACCCGATACATTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

Helix-hairpin-helix domain (HHH_5)

(538-585)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

89.456

97.674

0.874
  uvrC Streptococcus pneumoniae R6

89.116

97.674

0.87
  uvrC Streptococcus pneumoniae D39

89.116

97.674

0.87

Multiple sequence alignment