Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   HCC49_RS14465 Genome accession   NZ_CP050462
Coordinates   2943320..2943964 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain Htq6     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2938320..2948964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCC49_RS14430 (HCC49_14430) - 2939505..2939936 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  HCC49_RS14435 (HCC49_14435) - 2939936..2940277 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  HCC49_RS14440 (HCC49_14440) - 2940270..2941751 (+) 1482 WP_094247541.1 Na+/H+ antiporter subunit D -
  HCC49_RS14445 (HCC49_14445) - 2941757..2942233 (+) 477 WP_071392239.1 Na+/H+ antiporter subunit E -
  HCC49_RS14450 (HCC49_14450) - 2942233..2942517 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  HCC49_RS14455 (HCC49_14455) mnhG 2942501..2942875 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  HCC49_RS14460 (HCC49_14460) - 2942915..2943298 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  HCC49_RS14465 (HCC49_14465) comA 2943320..2943964 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  HCC49_RS14470 (HCC49_14470) comP 2944045..2946345 (-) 2301 WP_167860384.1 histidine kinase Regulator
  HCC49_RS14475 (HCC49_14475) comX 2946359..2946532 (-) 174 WP_102422026.1 competence pheromone ComX -
  HCC49_RS14480 (HCC49_14480) - 2946501..2947361 (-) 861 WP_167860385.1 polyprenyl synthetase family protein -
  HCC49_RS14485 (HCC49_14485) degQ 2947569..2947709 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  HCC49_RS14490 (HCC49_14490) - 2948174..2948515 (+) 342 WP_014305721.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=432975 HCC49_RS14465 WP_003152052.1 2943320..2943964(-) (comA) [Bacillus velezensis strain Htq6]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=432975 HCC49_RS14465 WP_003152052.1 2943320..2943964(-) (comA) [Bacillus velezensis strain Htq6]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTTAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGCAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCATGTGCTGAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGCTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCTGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGTACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864