Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   HB752_RS00105 Genome accession   NZ_CP050271
Coordinates   24947..25240 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 19947..30240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS00080 (HB752_00080) - 21852..22235 (+) 384 WP_002263434.1 DUF1033 family protein -
  HB752_RS00085 (HB752_00085) comYA 22365..23306 (+) 942 WP_019804919.1 competence type IV pilus ATPase ComGA Machinery gene
  HB752_RS00090 (HB752_00090) comGB 23242..24272 (+) 1031 Protein_12 competence type IV pilus assembly protein ComGB -
  HB752_RS00095 (HB752_00095) comYC 24272..24586 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  HB752_RS00100 (HB752_00100) comGD 24573..24975 (+) 403 Protein_14 competence type IV pilus minor pilin ComGD -
  HB752_RS00105 (HB752_00105) comYE 24947..25240 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  HB752_RS00110 (HB752_00110) comGF 25227..25660 (+) 434 Protein_16 competence type IV pilus minor pilin ComGF -
  HB752_RS00115 (HB752_00115) comYG 25638..26027 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  HB752_RS00120 (HB752_00120) comYH 26082..27035 (+) 954 WP_019317550.1 class I SAM-dependent methyltransferase Machinery gene
  HB752_RS00125 (HB752_00125) - 27094..28293 (+) 1200 WP_002263443.1 acetate kinase -
  HB752_RS00130 (HB752_00130) tnpA 28506..28969 (+) 464 Protein_20 IS200/IS605 family transposase -
  HB752_RS00135 (HB752_00135) - 29597..29842 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=431092 HB752_RS00105 WP_002263439.1 24947..25240(+) (comYE) [Streptococcus mutans strain S1]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=431092 HB752_RS00105 WP_002263439.1 24947..25240(+) (comYE) [Streptococcus mutans strain S1]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412