Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   HB752_RS00035 Genome accession   NZ_CP050271
Coordinates   6031..6513 (+) Length   160 a.a.
NCBI ID   WP_002263585.1    Uniprot ID   A0AAX1K1V7
Organism   Streptococcus mutans strain S1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1031..11513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS00035 (HB752_00035) comX/sigX 6031..6513 (+) 483 WP_002263585.1 sigma-70 family RNA polymerase sigma factor Regulator
  HB752_RS00040 (HB752_00040) ispE 6660..7508 (+) 849 WP_002263586.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  HB752_RS00045 (HB752_00045) - 8141..8587 (+) 447 WP_002281524.1 zinc-dependent MarR family transcriptional regulator -
  HB752_RS00050 (HB752_00050) - 8590..9300 (+) 711 WP_019804921.1 metal ABC transporter ATP-binding protein -
  HB752_RS00055 (HB752_00055) - 9290..10102 (+) 813 WP_002268886.1 metal ABC transporter permease -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19605.49 Da        Isoelectric Point: 6.4997

>NTDB_id=431087 HB752_RS00035 WP_002263585.1 6031..6513(+) (comX/sigX) [Streptococcus mutans strain S1]
MEEDFEIVFNKVKPIVWKLSRYYFIKMWTREDWQQEGMLILHQLLREHPELEEDDTKLYIYFKTRFSNYIKDVLRQQESQ
KRRFNRMSYEEVGEIEHCLSSGGMQLDEYILFRDSLLAYKQGLSTEKQELFERLVAGEHFLGRQSMLKDLRKKLSDFKEK

Nucleotide


Download         Length: 483 bp        

>NTDB_id=431087 HB752_RS00035 WP_002263585.1 6031..6513(+) (comX/sigX) [Streptococcus mutans strain S1]
ATGGAAGAAGATTTTGAAATTGTTTTTAATAAGGTTAAGCCAATTGTATGGAAATTAAGCCGTTATTACTTTATTAAAAT
GTGGACTCGTGAAGATTGGCAACAAGAGGGAATGTTGATTTTGCACCAATTATTAAGGGAACATCCAGAATTAGAAGAGG
ATGATACAAAATTGTATATCTATTTTAAGACACGTTTTTCTAATTACATTAAAGATGTTTTGCGTCAGCAAGAAAGTCAG
AAACGTCGTTTTAATAGAATGTCTTATGAAGAAGTCGGTGAGATTGAACACTGTTTGTCAAGTGGCGGTATGCAATTGGA
TGAATATATTTTATTTCGTGATAGTTTGCTTGCATATAAACAAGGTCTGAGTACTGAAAAGCAAGAGCTGTTTGAGCGCT
TGGTAGCAGGAGAGCACTTTTTGGGAAGGCAAAGTATGCTGAAAGATTTACGTAAAAAATTAAGTGATTTTAAGGAAAAA
TAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus mutans UA159

100

100

1
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

47.436

97.5

0.463
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

47.436

97.5

0.463
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

47.712

95.625

0.456
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

47.059

95.625

0.45
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

45.513

97.5

0.444
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

46.405

95.625

0.444
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

45.752

95.625

0.438
  comX/comX1 Streptococcus pneumoniae TIGR4

46

93.75

0.431
  comX/comX2 Streptococcus pneumoniae Rx1

46

93.75

0.431
  comX/comX1 Streptococcus pneumoniae Rx1

46

93.75

0.431
  comX/comX2 Streptococcus pneumoniae D39

46

93.75

0.431
  comX/comX1 Streptococcus pneumoniae D39

46

93.75

0.431
  comX/comX1 Streptococcus pneumoniae R6

46

93.75

0.431
  comX/comX2 Streptococcus pneumoniae R6

46

93.75

0.431
  comX/comX2 Streptococcus pneumoniae TIGR4

46

93.75

0.431
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

45.098

95.625

0.431
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

45.098

95.625

0.431
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

44.444

95.625

0.425
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

44.444

95.625

0.425
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

44.444

95.625

0.425
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

44.444

95.625

0.425
  comX/sigX Streptococcus suis P1/7

43.226

96.875

0.419
  comX/sigX Streptococcus suis isolate S10

43.226

96.875

0.419
  comX/sigX Streptococcus suis D9

43.226

96.875

0.419
  comX Streptococcus sobrinus strain NIDR 6715-7

42.581

96.875

0.413
  comX/sigX Streptococcus salivarius strain HSISS4

41.667

97.5

0.406
  comX Streptococcus salivarius SK126

41.667

97.5

0.406
  comX Streptococcus thermophilus LMD-9

41.026

97.5

0.4
  comX Streptococcus thermophilus LMG 18311

41.026

97.5

0.4