Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HA248_RS01920 Genome accession   NZ_CP050175
Coordinates   364468..365157 (+) Length   229 a.a.
NCBI ID   WP_033705362.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 359468..370157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS01895 (HA248_01890) gpsB 359578..359907 (+) 330 WP_000146522.1 cell division regulator GpsB -
  HA248_RS01905 (HA248_01900) - 360393..361550 (+) 1158 WP_033705364.1 class I SAM-dependent RNA methyltransferase -
  HA248_RS01910 (HA248_01905) mapZ 361562..362956 (+) 1395 WP_000039303.1 mid-cell-anchored protein MapZ -
  HA248_RS01915 (HA248_01910) gndA 363032..364456 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  HA248_RS01920 (HA248_01915) covR 364468..365157 (+) 690 WP_033705362.1 response regulator transcription factor Regulator
  HA248_RS01925 (HA248_01920) cbpC 365255..366271 (+) 1017 WP_033705361.1 choline-binding protein CbpC -
  HA248_RS01930 (HA248_01925) mvk 366393..367271 (+) 879 WP_000163323.1 mevalonate kinase -
  HA248_RS01935 (HA248_01930) mvaD 367253..368206 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  HA248_RS01940 (HA248_01935) - 368193..369200 (+) 1008 WP_033705360.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26958.32 Da        Isoelectric Point: 6.9836

>NTDB_id=430520 HA248_RS01920 WP_033705362.1 364468..365157(+) (covR) [Streptococcus pneumoniae strain PZ900701590]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALFMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=430520 HA248_RS01920 WP_033705362.1 364468..365157(+) (covR) [Streptococcus pneumoniae strain PZ900701590]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTTCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463