Detailed information NTG0430516

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: HA248_RS00265
• Genome accession: NZ_CP050175
• Coordinates: 46856..48205 (+)
• Length: 449 a.a.
• NCBI ID: WP_033707869.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701590
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 41856..53205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA248_RS00245 (HA248_00245)	-	42763..43245 (+)	483	WP_001232094.1	stage II sporulation protein M	-
HA248_RS00250 (HA248_00250)	-	43242..43838 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
HA248_RS00255 (HA248_00255)	-	43819..44310 (+)	492	WP_000671990.1	hypothetical protein	-
HA248_RS00260 (HA248_00260)	comA	44690..46843 (+)	2154	WP_033707870.1	peptide cleavage/export ABC transporter ComA	Regulator
HA248_RS00265 (HA248_00265)	comB	46856..48205 (+)	1350	WP_033707869.1	competence pheromone export protein ComB	Regulator
HA248_RS00270 (HA248_00270)	purC	48375..49082 (+)	708	WP_000043314.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
HA248_RS00275 (HA248_00275)	-	49139..52864 (+)	3726	WP_166735646.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49631.47 Da
• Isoelectric Point: 5.3895

>NTDB_id=430516 HA248_RS00265 WP_033707869.1 46856..48205(+) (comB) [Streptococcus pneumoniae strain PZ900701590]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSFAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=430516 HA248_RS00265 WP_033707869.1 46856..48205(+) (comB) [Streptococcus pneumoniae strain PZ900701590]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTACTTCCTTTGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCAAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTTCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
TCTACAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae Rx1	99.332	100	0.993
comB	Streptococcus pneumoniae D39	99.332	100	0.993
comB	Streptococcus pneumoniae R6	99.332	100	0.993
comB	Streptococcus pneumoniae TIGR4	99.109	100	0.991
comB	Streptococcus mitis SK321	94.655	100	0.947
comB	Streptococcus mitis NCTC 12261	94.209	100	0.942
comB	Streptococcus gordonii str. Challis substr. CH1	55.556	100	0.557