Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HBA50_RS07655 Genome accession   NZ_CP050133
Coordinates   1530335..1531024 (-) Length   229 a.a.
NCBI ID   WP_045498907.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1525335..1536024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS07630 (HBA50_07630) - 1525868..1526821 (-) 954 WP_045498916.1 ABC transporter ATP-binding protein -
  HBA50_RS07635 (HBA50_07635) - 1526821..1527417 (-) 597 WP_045498913.1 TetR/AcrR family transcriptional regulator -
  HBA50_RS07640 (HBA50_07640) - 1527657..1527758 (-) 102 Protein_1495 SAM-dependent methyltransferase -
  HBA50_RS07645 (HBA50_07645) - 1527865..1529478 (-) 1614 WP_045498910.1 ribonuclease Y -
  HBA50_RS07650 (HBA50_07650) - 1529756..1530238 (+) 483 WP_005590897.1 S-ribosylhomocysteine lyase -
  HBA50_RS07655 (HBA50_07655) covR 1530335..1531024 (-) 690 WP_045498907.1 response regulator transcription factor Regulator
  HBA50_RS07660 (HBA50_07660) gndA 1531034..1532458 (-) 1425 WP_045498904.1 NADP-dependent phosphogluconate dehydrogenase -
  HBA50_RS07665 (HBA50_07665) - 1532621..1534084 (-) 1464 WP_045498900.1 flotillin family protein -
  HBA50_RS07670 (HBA50_07670) - 1534266..1534949 (-) 684 WP_045498897.1 Bax inhibitor-1/YccA family protein -
  HBA50_RS07675 (HBA50_07675) - 1534969..1535460 (-) 492 WP_045498894.1 HD domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26508.55 Da        Isoelectric Point: 6.2793

>NTDB_id=430232 HBA50_RS07655 WP_045498907.1 1530335..1531024(-) (covR) [Streptococcus cristatus ATCC 51100]
MAKRILLVENEKNLARFVTLELQKEAFLLDVIETGSQGLALARENDYDLFLLNYDLQDMTASEFARQLSLFKPASVIIVL
ASREEIKEHADEIQRFAVSYTVKPFIISDLVEKVSDIFRGRDFIDQHCSKLKTPTAYRNLRVDLKNHIVYRGEEVIALTR
REYDLLVTLMSSPKVMSREQLLERVWKYEGATETNVVDVYIRYLRSKIDVAGQTSYIKTVRGIGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=430232 HBA50_RS07655 WP_045498907.1 1530335..1531024(-) (covR) [Streptococcus cristatus ATCC 51100]
ATGGCAAAGCGAATTTTATTAGTAGAAAATGAAAAGAATCTTGCACGATTTGTGACTTTGGAACTGCAAAAGGAAGCATT
TCTTTTGGATGTAATTGAGACAGGAAGTCAAGGTTTGGCACTAGCTAGAGAAAATGACTATGATCTATTTTTGCTTAATT
ATGACCTGCAGGATATGACTGCTAGTGAGTTTGCTAGGCAACTGAGTTTATTCAAGCCGGCCTCAGTCATTATCGTCTTA
GCCAGCCGTGAAGAGATCAAAGAACATGCAGATGAGATTCAGCGCTTTGCTGTTTCCTATACCGTCAAACCTTTTATTAT
CAGCGATTTGGTTGAGAAAGTATCCGATATCTTTCGAGGTCGGGACTTTATTGACCAGCATTGTAGCAAGCTAAAAACAC
CGACTGCTTACCGCAATCTACGAGTTGATTTGAAAAATCATATCGTCTATCGTGGAGAGGAAGTGATTGCCTTGACACGA
CGAGAATATGATCTATTAGTGACGCTGATGAGTAGTCCAAAAGTCATGAGTCGCGAGCAACTTCTAGAACGTGTCTGGAA
GTATGAAGGTGCCACTGAAACTAATGTAGTAGATGTCTATATTCGCTACCTACGTAGTAAGATTGATGTTGCTGGACAGA
CCAGCTATATCAAAACTGTCCGTGGTATCGGCTATGCTATGCAGGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.725

100

0.467