Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IF770_RS04775 Genome accession   NZ_CP062401
Coordinates   940551..942332 (-) Length   593 a.a.
NCBI ID   WP_240052733.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_OP_098     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 935551..947332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF770_RS04755 (IF770_04750) racE 935944..936744 (-) 801 WP_001039659.1 glutamate racemase -
  IF770_RS04760 (IF770_04755) sdhB 936980..937795 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  IF770_RS04765 (IF770_04760) sdhA 937795..939561 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  IF770_RS04770 (IF770_04765) - 939613..940227 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  IF770_RS04775 (IF770_04770) uvrC 940551..942332 (-) 1782 WP_240052733.1 excinuclease ABC subunit UvrC Machinery gene
  IF770_RS04780 (IF770_04775) - 942498..942593 (+) 96 WP_001788625.1 hypothetical protein -
  IF770_RS04785 (IF770_04780) trxA 942656..942970 (-) 315 WP_001018928.1 thioredoxin -
  IF770_RS04790 (IF770_04785) mutS/mutS2 943143..945491 (-) 2349 WP_001249272.1 endonuclease MutS2 Machinery gene
  IF770_RS04795 (IF770_04790) polX 945501..947213 (-) 1713 WP_000161938.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68703.42 Da        Isoelectric Point: 9.7464

>NTDB_id=429087 IF770_RS04775 WP_240052733.1 940551..942332(-) (uvrC) [Staphylococcus aureus strain NAS_OP_098]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKSKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=429087 IF770_RS04775 WP_240052733.1 940551..942332(-) (uvrC) [Staphylococcus aureus strain NAS_OP_098]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAATCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATTGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCAAGAACGATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTCGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCATCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565