Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IF703_RS05080 Genome accession   NZ_CP062382
Coordinates   995680..997461 (-) Length   593 a.a.
NCBI ID   WP_000390515.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_AN_068     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 990680..1002461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF703_RS05060 (IF703_05010) racE 991070..991870 (-) 801 WP_001039651.1 glutamate racemase -
  IF703_RS05065 (IF703_05015) sdhB 992109..992924 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  IF703_RS05070 (IF703_05020) sdhA 992924..994690 (-) 1767 WP_031927766.1 succinate dehydrogenase flavoprotein subunit -
  IF703_RS05075 (IF703_05025) - 994742..995356 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  IF703_RS05080 (IF703_05030) uvrC 995680..997461 (-) 1782 WP_000390515.1 excinuclease ABC subunit UvrC Machinery gene
  IF703_RS05085 (IF703_05035) - 997627..997722 (+) 96 WP_001803554.1 hypothetical protein -
  IF703_RS05090 (IF703_05040) trxA 997785..998099 (-) 315 WP_001018928.1 thioredoxin -
  IF703_RS05095 (IF703_05045) mutS/mutS2 998272..1000620 (-) 2349 WP_001249271.1 endonuclease MutS2 Machinery gene
  IF703_RS05100 (IF703_05050) polX 1000630..1002342 (-) 1713 WP_000161948.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68657.38 Da        Isoelectric Point: 9.8215

>NTDB_id=428201 IF703_RS05080 WP_000390515.1 995680..997461(-) (uvrC) [Staphylococcus aureus strain NAS_AN_068]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLIGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLNKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=428201 IF703_RS05080 WP_000390515.1 995680..997461(-) (uvrC) [Staphylococcus aureus strain NAS_AN_068]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGCTTGCGATCGTATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGATTGGAGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACCGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCCTTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGTTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGAATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGATGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCGGATTTAATTA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATCCTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae R6

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae D39

57.094

98.651

0.563