Detailed information NTG0427939

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: G9P47_RS05485
• Genome accession: NZ_CP049802
• Coordinates: 1123660..1124703 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain Cap 100.1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1118660..1129703

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G9P47_RS05460 (G9P47_05480)	-	1119716..1120441 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
G9P47_RS05465 (G9P47_05485)	-	1120509..1121495 (-)	987	WP_235065955.1	FUSC family protein	-
G9P47_RS05470 (G9P47_05490)	map	1121662..1122417 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
G9P47_RS05475 (G9P47_05495)	-	1122561..1122947 (+)	387	WP_002466133.1	DUF2543 family protein	-
G9P47_RS05480 (G9P47_05500)	liaF	1122962..1123663 (+)	702	WP_002466140.1	cell wall-active antibiotics response protein LiaF	-
G9P47_RS05485 (G9P47_05505)	vraS	1123660..1124703 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
G9P47_RS05490 (G9P47_05510)	vraR	1124693..1125322 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
G9P47_RS05495 (G9P47_05515)	-	1125381..1126616 (-)	1236	WP_002466159.1	YihY/virulence factor BrkB family protein	-
G9P47_RS05500 (G9P47_05520)	-	1126846..1127130 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
G9P47_RS05505 (G9P47_05525)	-	1127137..1127601 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
G9P47_RS05510 (G9P47_05530)	-	1127748..1127951 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
G9P47_RS05515 (G9P47_05535)	-	1127964..1129205 (+)	1242	WP_002466147.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=427939 G9P47_RS05485 WP_002466111.1 1123660..1124703(+) (vraS) [Staphylococcus warneri strain Cap 100.1]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=427939 G9P47_RS05485 WP_002466111.1 1123660..1124703(+) (vraS) [Staphylococcus warneri strain Cap 100.1]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948