Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MYY_RS02390 Genome accession   NC_017769
Coordinates   439471..440103 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae ST556     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 434471..445103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYY_RS02365 (MYY_0461) mvaD 434748..435701 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  MYY_RS02370 (MYY_0462) - 435688..436695 (+) 1008 WP_000562377.1 phosphomevalonate kinase -
  MYY_RS02375 (MYY_0463) fni 436679..437689 (+) 1011 WP_000210628.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  MYY_RS02380 (MYY_0464) liaF 437767..438465 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  MYY_RS02385 (MYY_0465) - 438462..439457 (+) 996 WP_000743662.1 sensor histidine kinase -
  MYY_RS02390 (MYY_0466) vraR 439471..440103 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  MYY_RS13525 - 440104..440346 (+) 243 Protein_477 DNA alkylation repair protein -
  MYY_RS13220 - 440271..440873 (+) 603 Protein_478 DNA alkylation repair protein -
  MYY_RS02410 (MYY_0470) - 441332..441934 (+) 603 Protein_479 trypsin-like serine peptidase -
  MYY_RS02415 (MYY_0471) - 442236..442595 (+) 360 WP_000378123.1 tyrosine-type recombinase/integrase -
  MYY_RS02420 (MYY_0472) tig 442789..444072 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=42767 MYY_RS02390 WP_000698433.1 439471..440103(+) (vraR) [Streptococcus pneumoniae ST556]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=42767 MYY_RS02390 WP_000698433.1 439471..440103(+) (vraR) [Streptococcus pneumoniae ST556]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment