Detailed information NTG0426766

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: G8B44_RS07300
• Genome accession: NZ_CP049688
• Coordinates: 1451064..1452065 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain ABC245
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1446064..1457065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G8B44_RS07285 (G8B44_07320)	thrS	1446234..1448177 (-)	1944	WP_011528363.1	threonine--tRNA ligase	-
G8B44_RS07290 (G8B44_07325)	-	1448599..1449933 (-)	1335	WP_011528362.1	glycosyltransferase family 4 protein	-
G8B44_RS07295 (G8B44_07330)	-	1449935..1450933 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
G8B44_RS07300 (G8B44_07335)	ccpA	1451064..1452065 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
G8B44_RS07305 (G8B44_07340)	-	1452239..1453324 (+)	1086	WP_011528361.1	aminopeptidase P family protein	-
G8B44_RS07310 (G8B44_07345)	-	1453373..1454038 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
G8B44_RS07315 (G8B44_07350)	-	1454049..1454426 (+)	378	WP_002985686.1	VOC family protein	-
G8B44_RS07320 (G8B44_07355)	-	1454571..1455497 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
G8B44_RS07325 (G8B44_07360)	-	1455708..1456391 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=426766 G8B44_RS07300 WP_002985680.1 1451064..1452065(-) (ccpA) [Streptococcus pyogenes strain ABC245]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=426766 G8B44_RS07300 WP_002985680.1 1451064..1452065(-) (ccpA) [Streptococcus pyogenes strain ABC245]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559