Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IHN46_RS09820 Genome accession   NZ_CP062249
Coordinates   1989383..1990039 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain AML002_ev01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1984383..1995039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IHN46_RS09790 yecA 1985634..1986299 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  IHN46_RS09810 pgsA 1986949..1987497 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IHN46_RS09815 uvrC 1987554..1989386 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IHN46_RS09820 letA 1989383..1990039 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IHN46_RS22750 - 1990181..1990252 (+) 72 Protein_1950 transcriptional regulator -
  IHN46_RS09825 yecU 1990335..1990511 (+) 177 WP_000590347.1 protein YecU -
  IHN46_RS09830 yecF 1990498..1990722 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IHN46_RS09835 sdiA 1990790..1991512 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  IHN46_RS09840 tcyN 1991742..1992494 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IHN46_RS09845 tcyL 1992491..1993159 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IHN46_RS09850 dcyD 1993174..1994160 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=425176 IHN46_RS09820 WP_000611335.1 1989383..1990039(-) (letA) [Escherichia coli strain AML002_ev01]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=425176 IHN46_RS09820 WP_000611335.1 1989383..1990039(-) (letA) [Escherichia coli strain AML002_ev01]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486