Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IHN50_RS09810 Genome accession   NZ_CP062245
Coordinates   1988183..1988839 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain AML003_ev01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1983183..1993839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IHN50_RS09780 yecA 1984434..1985099 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  IHN50_RS09800 pgsA 1985749..1986297 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IHN50_RS09805 uvrC 1986354..1988186 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IHN50_RS09810 letA 1988183..1988839 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IHN50_RS22740 - 1988981..1989052 (+) 72 Protein_1948 transcriptional regulator -
  IHN50_RS09815 yecU 1989135..1989311 (+) 177 WP_000590347.1 protein YecU -
  IHN50_RS09820 yecF 1989298..1989522 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IHN50_RS09825 sdiA 1989590..1990312 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  IHN50_RS09830 tcyN 1990542..1991294 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IHN50_RS09835 tcyL 1991291..1991959 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IHN50_RS09840 dcyD 1991974..1992960 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=424848 IHN50_RS09810 WP_000611335.1 1988183..1988839(-) (letA) [Escherichia coli strain AML003_ev01]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=424848 IHN50_RS09810 WP_000611335.1 1988183..1988839(-) (letA) [Escherichia coli strain AML003_ev01]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486