Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ST64987_RS02935 Genome accession   NZ_CP049053
Coordinates   541027..542253 (+) Length   408 a.a.
NCBI ID   WP_084828584.1    Uniprot ID   A0A0E2Q2Z7
Organism   Streptococcus thermophilus strain ST64987     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 536027..547253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS02910 (ST64987_0534) - 536602..537873 (-) 1272 WP_167401450.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ST64987_RS02915 (ST64987_0535) - 537866..539041 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  ST64987_RS02920 (ST64987_0536) - 539363..540223 (+) 861 WP_002950145.1 thymidylate synthase -
  ST64987_RS02925 (ST64987_0537) - 540331..540834 (+) 504 WP_002950147.1 dihydrofolate reductase -
  ST64987_RS02930 (ST64987_0538) - 540839..541009 (+) 171 WP_002886174.1 hypothetical protein -
  ST64987_RS02935 (ST64987_0539) clpX 541027..542253 (+) 1227 WP_084828584.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ST64987_RS02940 (ST64987_0540) yihA 542263..542862 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ST64987_RS02945 (ST64987_0541) - 542991..544367 (+) 1377 WP_167401451.1 amino acid permease -
  ST64987_RS02950 (ST64987_0542) mmuM 544379..545329 (+) 951 WP_011680907.1 homocysteine S-methyltransferase -
  ST64987_RS02955 (ST64987_0543) - 545442..545696 (+) 255 WP_002950164.1 DUF1912 family protein -
  ST64987_RS02960 (ST64987_0544) - 545767..546126 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  ST64987_RS02965 (ST64987_0545) plsY 546240..546881 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45071.48 Da        Isoelectric Point: 4.4429

>NTDB_id=424470 ST64987_RS02935 WP_084828584.1 541027..542253(+) (clpX) [Streptococcus thermophilus strain ST64987]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDHDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSQEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=424470 ST64987_RS02935 WP_084828584.1 541027..542253(+) (clpX) [Streptococcus thermophilus strain ST64987]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATCATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGCGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCAGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q2Z7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.998

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566