Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ST64987_RS01680 Genome accession   NZ_CP049053
Coordinates   299896..301413 (+) Length   505 a.a.
NCBI ID   WP_167401421.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 294896..306413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS10070 - 295176..295346 (+) 171 Protein_265 ascorbate 6-phosphate lactonase -
  ST64987_RS01655 (ST64987_0292) - 295363..296034 (-) 672 WP_064355629.1 TrkA family potassium uptake protein -
  ST64987_RS01660 (ST64987_0293) - 296074..297438 (-) 1365 WP_081247984.1 TrkH family potassium uptake protein -
  ST64987_RS01665 (ST64987_0294) rsmG 297508..298221 (-) 714 WP_100273329.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ST64987_RS01670 (ST64987_0295) - 298518..299054 (+) 537 WP_100273690.1 DUF177 domain-containing protein -
  ST64987_RS01675 (ST64987_0296) covR 299210..299899 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  ST64987_RS01680 (ST64987_0297) covS 299896..301413 (+) 1518 WP_167401421.1 HAMP domain-containing histidine kinase Regulator
  ST64987_RS01685 (ST64987_0298) nrdR 301536..302015 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  ST64987_RS01690 (ST64987_0299) - 302012..303187 (+) 1176 WP_167401422.1 DnaD domain protein -
  ST64987_RS01695 (ST64987_0300) dnaI 303191..304093 (+) 903 WP_002946786.1 primosomal protein DnaI -
  ST64987_RS01700 (ST64987_0301) der 304199..305509 (+) 1311 WP_095559237.1 ribosome biogenesis GTPase Der -
  ST64987_RS09790 - 305573..306241 (+) 669 Protein_276 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57534.02 Da        Isoelectric Point: 5.5179

>NTDB_id=424461 ST64987_RS01680 WP_167401421.1 299896..301413(+) (covS) [Streptococcus thermophilus strain ST64987]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=424461 ST64987_RS01680 WP_167401421.1 299896..301413(+) (covS) [Streptococcus thermophilus strain ST64987]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.422

99.406

0.939