Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IFO96_RS13345 Genome accession   NZ_CP062211
Coordinates   2748562..2749218 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain L3Cip3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2743562..2754218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IFO96_RS13315 (IFO96_13315) yecA 2744813..2745478 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  IFO96_RS13335 (IFO96_13335) pgsA 2746128..2746676 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IFO96_RS13340 (IFO96_13340) uvrC 2746733..2748565 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IFO96_RS13345 (IFO96_13345) letA 2748562..2749218 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IFO96_RS26815 - 2749360..2749431 (+) 72 Protein_2640 transcriptional regulator -
  IFO96_RS13350 (IFO96_13350) yecU 2749514..2749690 (+) 177 WP_000590347.1 protein YecU -
  IFO96_RS13355 (IFO96_13355) yecF 2749677..2749901 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IFO96_RS13360 (IFO96_13360) sdiA 2749969..2750691 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  IFO96_RS13365 (IFO96_13365) tcyN 2750921..2751673 (-) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IFO96_RS13370 (IFO96_13370) tcyL 2751670..2752338 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IFO96_RS13375 (IFO96_13375) dcyD 2752353..2753339 (-) 987 WP_001128218.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=424100 IFO96_RS13345 WP_000611335.1 2748562..2749218(-) (letA) [Escherichia coli strain L3Cip3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=424100 IFO96_RS13345 WP_000611335.1 2748562..2749218(-) (letA) [Escherichia coli strain L3Cip3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486