Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IE857_RS09795 Genome accession   NZ_CP061914
Coordinates   2047942..2048598 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SMBL     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2042942..2053598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IE857_RS09765 (IE857_09765) dcyD 2043822..2044808 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  IE857_RS09770 (IE857_09770) tcyL 2044823..2045491 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IE857_RS09775 (IE857_09775) tcyN 2045488..2046240 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IE857_RS09780 (IE857_09780) sdiA 2046470..2047192 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  IE857_RS09785 (IE857_09785) yecF 2047259..2047483 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IE857_RS09790 (IE857_09790) yecU 2047470..2047646 (-) 177 WP_000590347.1 protein YecU -
  IE857_RS24525 - 2047729..2047800 (-) 72 Protein_1934 transcriptional regulator -
  IE857_RS09795 (IE857_09795) letA 2047942..2048598 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IE857_RS09800 (IE857_09800) uvrC 2048595..2050427 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IE857_RS09805 (IE857_09805) pgsA 2050484..2051032 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IE857_RS09825 (IE857_09825) yecA 2051682..2052347 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=423606 IE857_RS09795 WP_000611335.1 2047942..2048598(+) (letA) [Escherichia coli strain SMBL]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=423606 IE857_RS09795 WP_000611335.1 2047942..2048598(+) (letA) [Escherichia coli strain SMBL]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486