Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   G3T13_RS08840 Genome accession   NZ_CP048686
Coordinates   1811945..1814059 (+) Length   704 a.a.
NCBI ID   WP_061775525.1    Uniprot ID   -
Organism   Lactococcus raffinolactis strain KACC 13441     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1806894..1815752 1811945..1814059 within 0


Gene organization within MGE regions


Location: 1806894..1815752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3T13_RS08805 - 1807328..1808677 (-) 1350 WP_061775514.1 FAD-dependent oxidoreductase -
  G3T13_RS08810 - 1808695..1809081 (-) 387 WP_061775515.1 iron-sulfur cluster biosynthesis family protein -
  G3T13_RS08815 - 1809107..1809730 (-) 624 WP_002355386.1 cysteine hydrolase -
  G3T13_RS08820 - 1809757..1809921 (-) 165 WP_163604811.1 hypothetical protein -
  G3T13_RS08825 - 1810004..1810585 (-) 582 WP_061775517.1 TetR/AcrR family transcriptional regulator -
  G3T13_RS08830 - 1810780..1811460 (-) 681 WP_163604812.1 IS6-like element ISS1N family transposase -
  G3T13_RS08835 - 1811536..1811673 (-) 138 Protein_1729 integrase core domain-containing protein -
  G3T13_RS08840 clpC 1811945..1814059 (+) 2115 WP_061775525.1 ATP-dependent protease ClpL Regulator
  G3T13_RS08845 - 1814190..1814552 (-) 363 Protein_1731 transposase -
  G3T13_RS08850 - 1814545..1814797 (-) 253 Protein_1732 integrase core domain-containing protein -
  G3T13_RS08855 - 1814883..1815017 (+) 135 Protein_1733 IS5/IS1182 family transposase -
  G3T13_RS08860 - 1815072..1815752 (-) 681 WP_047916692.1 IS6-like element ISS1N family transposase -

Sequence

Protein


Download         Length: 704 a.a.        Molecular weight: 77767.20 Da        Isoelectric Point: 4.8394

>NTDB_id=422296 G3T13_RS08840 WP_061775525.1 1811945..1814059(+) (clpC) [Lactococcus raffinolactis strain KACC 13441]
MANFNGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTPDEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGIL
EKLGTNLTEQARDGLLDPVIGRENEIQETAEILSRRTKNNAILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSID
LSSLEAGTQYRGSFEENIKQLVEEVKAAGNIILFFDEIHQILGTGATGGEDGGKGLADIIKPALSRGELSVIGATTQDEY
RNTILKNAALARRFNDVVINEPTAADTLRILQGIKELYEKHHHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAA
HLAAKNSQTDVETLDQRLKKLEAAKEAAIKAEDFTKAADIKKSIEETKQKIKETDQKEKITATIDDVAQSVERLTGIPVS
DMGANDIERLKNLDKRLKSMVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPTGVGKTELAKQLALDMFGNENAI
IRLDMSEYADRIAVSKLIGTSAGYVGYEDNANTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIN
FKNTIIIATSNAGFGNEALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLAKKSIK
LEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADLVDAEIVISAA

Nucleotide


Download         Length: 2115 bp        

>NTDB_id=422296 G3T13_RS08840 WP_061775525.1 1811945..1814059(+) (clpC) [Lactococcus raffinolactis strain KACC 13441]
ATGGCAAATTTCAACGGAAATGATCCTTTTTTCAACAATGATATGGATGATGTTTTCAATCAATTATTTCGGCGCATGGA
TAATCAAAATTCGGAGCGTGCGCGGTATTTAGTTAATGGACAATCGTTAACACCGGATGAGTTTGCTCAATACCGAGCAA
CTGGCAAGCTACCCCAAAATAATAAAACAATAGAAGTATCTAAAGATGGTAAACAGGCTGTTAAAAAAGGAGGGATTTTA
GAAAAGTTAGGGACTAATTTGACGGAACAGGCTCGTGATGGATTACTAGATCCAGTGATTGGACGTGAGAATGAGATTCA
AGAAACTGCAGAAATTTTGAGTCGTAGAACGAAAAATAATGCAATCTTAGTTGGTGATGCCGGTGTAGGTAAAACTGCAG
TCGTCGAAGGTCTGGCACAAGCAATTGTGGCTGGTAAAGTTCCAGAAACGATTCAAGATAAAGAAATCTATTCGATTGAT
TTATCGTCTTTGGAAGCGGGAACTCAATATCGCGGTTCTTTTGAAGAAAATATTAAACAGCTGGTAGAGGAAGTCAAAGC
AGCTGGTAATATTATTCTATTCTTCGATGAAATTCATCAGATTCTCGGCACGGGTGCCACTGGTGGTGAAGATGGTGGCA
AAGGATTGGCTGATATCATTAAACCTGCTTTGTCACGTGGCGAGCTGAGTGTAATCGGGGCTACGACTCAAGATGAATAT
CGCAATACTATTTTGAAAAATGCGGCTTTGGCACGGCGATTCAATGATGTTGTGATTAATGAACCGACGGCCGCTGACAC
TTTACGTATATTACAAGGTATTAAAGAGCTGTACGAAAAACATCATCATGTTGTATTACCAGATGATGTTTTGAAGGCGG
CTGTGGATTATTCAATCCAATATATACCACAACGCACTTTGCCAGATAAAGCTATCGATTTGATCGACATGACTGCGGCT
CATTTAGCGGCTAAAAATTCGCAAACTGATGTTGAGACATTGGATCAACGCCTTAAAAAATTAGAGGCAGCTAAGGAGGC
CGCCATTAAAGCGGAGGACTTTACAAAAGCTGCTGATATCAAGAAGTCGATCGAGGAAACCAAGCAAAAAATTAAAGAAA
CGGATCAAAAAGAAAAAATCACTGCCACGATTGATGATGTGGCACAATCGGTTGAACGTTTAACTGGTATACCAGTTTCT
GATATGGGCGCTAATGATATTGAGCGCTTGAAAAATCTTGATAAGCGTCTGAAAAGTATGGTAATCGGTCAAGATGAAGC
GGTTGAAATGGTAGCAAAAGCAATTCGGCGTAACCGTGCGGGCTTTTCAGAGGGTGATCAACCGATTGGAAGTTTTCTGT
TTGTGGGCCCAACTGGCGTAGGAAAGACTGAATTAGCTAAGCAATTAGCCTTAGATATGTTTGGAAATGAAAATGCGATT
ATTCGGCTAGATATGAGTGAATATGCTGATCGTATAGCTGTGTCGAAATTAATTGGTACCTCGGCTGGATACGTAGGCTA
TGAAGATAATGCTAATACTCTAACTGAACGGGTTCGGCGTAATCCATATTCCATTGTATTATTAGATGAAATTGAAAAGG
CTGATCCACAAGTGTTAACGTTACTGTTACAAGTGATGGATGATGGGCGCTTAACGGATGGACAAGGCAATGTCATTAAT
TTCAAAAATACGATTATTATTGCTACTTCTAATGCTGGCTTTGGTAATGAAGCATTAAGTGGTGACAAGCAACGAGATCA
GTCATTAATGGATAAGTTAGCACCATTTTTCCGCCCAGAATTTCTGAACCGTTTTAATGGAATCGTGGAATTTTCACATC
TGACTAAGCAAGACTTAAGTCAAATTGTCGATTTGATGTTGGCGGATGTACAAAAAACTTTAGCCAAAAAATCCATCAAA
CTTGAGGTAACTAAAGCGGCTAAAGATTGGCTGATGGAACAAGGCTATGATGAAGCAATGGGTGCGCGGCCATTACGGCG
AGTAATTGAACAACAAATTCGTGATAAGGTAACGGATTTCTACCTTGACCACTTAGATGTCAAAAACTTGAAGGCTGATT
TAGTGGATGCTGAGATTGTGATATCGGCAGCTTAG

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(264-362)

ATPase family associated with various cellular activities (AAA) (AAA)

(122-254)

AAA domain (Cdc48 subfamily) (AAA_2)

(447-606)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(614-684)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

48.096

100

0.484
  clpE Streptococcus pneumoniae TIGR4

51.763

88.636

0.459
  clpE Streptococcus pneumoniae R6

51.603

88.636

0.457
  clpE Streptococcus pneumoniae D39

51.603

88.636

0.457
  clpE Streptococcus pneumoniae Rx1

51.603

88.636

0.457
  clpE Streptococcus mutans UA159

50.392

90.483

0.456
  clpC Bacillus subtilis subsp. subtilis str. 168

45.994

88.636

0.408
  clpC Streptococcus pneumoniae Rx1

43.465

90.199

0.392
  clpC Streptococcus pneumoniae D39

43.465

90.199

0.392
  clpC Streptococcus thermophilus LMG 18311

44.733

87.642

0.392
  clpC Streptococcus thermophilus LMD-9

44.571

87.642

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.472

0.391
  clpC Streptococcus mutans UA159

44.032

88.068

0.388
  clpC Streptococcus pneumoniae TIGR4

43.76

87.642

0.384

Multiple sequence alignment