Detailed information NTG0422016

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GAU34_RS06160
• Genome accession: NZ_CP048643
• Coordinates: 1245822..1246808 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain SR153
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1240822..1251808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GAU34_RS06135 (GAU34_06135)	opp4B	1241036..1241998 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
GAU34_RS06140 (GAU34_06140)	opp4C	1242010..1242891 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
GAU34_RS06145 (GAU34_06145)	trpS	1242933..1243922 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
GAU34_RS06150 (GAU34_06150)	spxA	1244216..1244611 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
GAU34_RS06155 (GAU34_06155)	mecA	1244982..1245701 (+)	720	WP_001217728.1	adaptor protein MecA	-
GAU34_RS06160 (GAU34_06160)	coiA	1245822..1246808 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
GAU34_RS06165 (GAU34_06165)	pepF	1246856..1248664 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
GAU34_RS06170 (GAU34_06170)	yjbH	1249124..1249930 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
GAU34_RS06175 (GAU34_06175)	-	1249953..1250318 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
GAU34_RS06180 (GAU34_06180)	-	1250422..1251015 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
GAU34_RS06185 (GAU34_06185)	-	1251201..1251547 (+)	347	Protein_1226	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=422016 GAU34_RS06160 WP_000959282.1 1245822..1246808(+) (coiA) [Staphylococcus aureus strain SR153]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=422016 GAU34_RS06160 WP_000959282.1 1245822..1246808(+) (coiA) [Staphylococcus aureus strain SR153]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976