Detailed information NTG0042099

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: LCGT_RS02175
• Genome accession: NC_015930
• Coordinates: 445958..447448 (+)
• Length: 496 a.a.
• NCBI ID: WP_014024351.1
• Uniprot ID: A0AA46TWW1
• Organism: Lactococcus garvieae ATCC 49156
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 440958..452448

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LCGT_RS02150 (LCGT_0425)	pfkB	441105..442031 (+)	927	WP_004259111.1	1-phosphofructokinase	-
LCGT_RS02155 (LCGT_0426)	-	442046..443950 (+)	1905	WP_014024348.1	PTS fructose transporter subunit IIABC	-
LCGT_RS02160 (LCGT_0427)	-	444062..444304 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
LCGT_RS02165 (LCGT_0428)	-	444521..445072 (+)	552	WP_014024349.1	YceD family protein	-
LCGT_RS02170 (LCGT_0429)	covR	445174..445869 (+)	696	WP_014024350.1	response regulator transcription factor	Regulator
LCGT_RS02175 (LCGT_0430)	covS	445958..447448 (+)	1491	WP_014024351.1	HAMP domain-containing histidine kinase	Regulator
LCGT_RS02180 (LCGT_0431)	-	447845..449416 (+)	1572	WP_014024352.1	ABC transporter permease subunit	-
LCGT_RS02185 (LCGT_0432)	-	449417..450154 (+)	738	WP_014024353.1	amino acid ABC transporter ATP-binding protein	-
LCGT_RS02190 (LCGT_0433)	murD	450293..451654 (+)	1362	WP_014024354.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56753.73 Da
• Isoelectric Point: 5.1966

>NTDB_id=42099 LCGT_RS02175 WP_014024351.1 445958..447448(+) (covS) [Lactococcus garvieae ATCC 49156]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=42099 LCGT_RS02175 WP_014024351.1 445958..447448(+) (covS) [Lactococcus garvieae ATCC 49156]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCCTAGAAATTATTGCTCTCTTTATCGCTCAGTTTGTTGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACGATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.936	100	0.56