Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   IB936_RS08840 Genome accession   NZ_CP061133
Coordinates   1787939..1788535 (-) Length   198 a.a.
NCBI ID   WP_002992186.1    Uniprot ID   P0DF49
Organism   Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1782939..1793535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IB936_RS08805 (IB936_08805) - 1782999..1783304 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  IB936_RS08810 (IB936_08810) ruvX 1783316..1783735 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  IB936_RS08815 (IB936_08815) - 1783732..1784001 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  IB936_RS08820 (IB936_08820) spx 1784115..1784513 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  IB936_RS08825 (IB936_08825) recA 1784804..1785940 (-) 1137 WP_002992179.1 recombinase RecA -
  IB936_RS08830 (IB936_08830) cinA 1786029..1787300 (-) 1272 WP_002992182.1 competence/damage-inducible protein A Machinery gene
  IB936_RS08835 (IB936_08835) - 1787369..1787929 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  IB936_RS08840 (IB936_08840) ruvA 1787939..1788535 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA Machinery gene
  IB936_RS08845 (IB936_08845) - 1788537..1789757 (-) 1221 WP_011529098.1 MDR family MFS transporter -
  IB936_RS08850 (IB936_08850) hexB 1789768..1791750 (-) 1983 WP_021299132.1 DNA mismatch repair endonuclease MutL Machinery gene
  IB936_RS08855 (IB936_08855) - 1791845..1792990 (-) 1146 WP_021299091.1 tyrosine-type recombinase/integrase -
  IB936_RS08860 (IB936_08860) - 1793193..1793336 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21879.26 Da        Isoelectric Point: 6.8838

>NTDB_id=420482 IB936_RS08840 WP_002992186.1 1787939..1788535(-) (ruvA) [Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=420482 IB936_RS08840 WP_002992186.1 1787939..1788535(-) (ruvA) [Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

40.887

100

0.419

Multiple sequence alignment