Detailed information NTG0420153

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: GYN06_RS08530
• Genome accession: NZ_CP048246
• Coordinates: 1639437..1640297 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain CT602
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1634437..1645297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GYN06_RS08515 (GYN06_08280)	dapD	1634947..1635768 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
GYN06_RS08520 (GYN06_08285)	pgi	1635978..1637621 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
GYN06_RS08525 (GYN06_08290)	pilG	1638131..1639363 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
GYN06_RS08530 (GYN06_08295)	pilD	1639437..1640297 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
GYN06_RS08535 (GYN06_08300)	coaE	1640294..1640926 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
GYN06_RS08540 (GYN06_08305)	-	1640919..1641128 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
GYN06_RS08545 (GYN06_08310)	pilF	1641214..1642890 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
GYN06_RS08555 (GYN06_08320)	-	1643228..1643674 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
GYN06_RS08560 (GYN06_08325)	-	1643678..1644652 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
GYN06_RS08565 (GYN06_08335)	rplU	1644876..1645184 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=420153 GYN06_RS08530 WP_003689814.1 1639437..1640297(+) (pilD) [Neisseria gonorrhoeae strain CT602]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=420153 GYN06_RS08530 WP_003689814.1 1639437..1640297(+) (pilD) [Neisseria gonorrhoeae strain CT602]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441