Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SPPN_RS07595 Genome accession   NC_015875
Coordinates   1473605..1474837 (-) Length   410 a.a.
NCBI ID   WP_014017308.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1473009..1485941 1473605..1474837 within 0


Gene organization within MGE regions


Location: 1473009..1485941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS07590 (SPPN_07700) yihA 1473009..1473596 (-) 588 WP_000422580.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SPPN_RS07595 (SPPN_07705) clpX 1473605..1474837 (-) 1233 WP_014017308.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SPPN_RS13455 (SPPN_07710) - 1474874..1475044 (-) 171 WP_000442260.1 hypothetical protein -
  SPPN_RS07605 (SPPN_07715) - 1475044..1475550 (-) 507 WP_000162454.1 dihydrofolate reductase -
  SPPN_RS07610 (SPPN_07720) - 1475680..1476198 (-) 519 WP_014017309.1 Dps family protein -
  SPPN_RS07615 (SPPN_07725) lytC 1476435..1477925 (-) 1491 WP_080564677.1 choline binding-anchored murein hydrolase LytC -
  SPPN_RS07620 (SPPN_07730) tpiA 1477963..1478721 (-) 759 WP_000087892.1 triose-phosphate isomerase -
  SPPN_RS07625 (SPPN_07735) - 1478819..1479496 (-) 678 WP_000221602.1 DnaD domain-containing protein -
  SPPN_RS07630 (SPPN_07740) metA 1479505..1480449 (-) 945 WP_001122719.1 homoserine O-acetyltransferase MetA -
  SPPN_RS13985 - 1480515..1480685 (-) 171 WP_050241508.1 hypothetical protein -
  SPPN_RS07640 (SPPN_07745) - 1480830..1481342 (-) 513 WP_001049318.1 adenine phosphoribosyltransferase -
  SPPN_RS07645 (SPPN_07750) - 1481615..1482745 (-) 1131 WP_000229957.1 ABC transporter ATP-binding protein -
  SPPN_RS07655 (SPPN_07755) - 1483200..1483775 (-) 576 WP_000158736.1 cysteine hydrolase family protein -
  SPPN_RS07660 (SPPN_07760) codY 1483775..1484563 (-) 789 WP_000940732.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  SPPN_RS07665 (SPPN_07765) - 1484775..1485941 (+) 1167 WP_000160552.1 IS30 family transposase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45638.18 Da        Isoelectric Point: 4.4481

>NTDB_id=42008 SPPN_RS07595 WP_014017308.1 1473605..1474837(-) (clpX) [Streptococcus pseudopneumoniae IS7493]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEGVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=42008 SPPN_RS07595 WP_014017308.1 1473605..1474837(-) (clpX) [Streptococcus pseudopneumoniae IS7493]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGCAACAATGCCTTTATTTGTAATGAATGCGTGGAGTTAGCTCAAGAAATTATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCAGTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGG
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGGCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTTAAACTCTTGCAGGCTGCTGACTTTAACATTGAGCGCGCAGAGCGTGGGATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGCGAGAACGTGTCTATCACACGGGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAAGGAACAGTTGCTAGCGTACCACCTCAAGGTGGACGCAAACATCCGCAACAAGAAATGATTCAAGTAGATACC
AAGAATATCCTCTTCATTGTTGGTGGTGCCTTTGATGGTATTGAAGAAATTGTTAAACAACGTCTTGGAGAAAAAGTCAT
CGGATTTGGTCAAAATAACAAGGCGATTGATGAAAATAGCTCTTACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGTTTGCCTGTCTTTGCAGCTCTTGAGCAATTGACGGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAATATCAAACCTTGCTTTCTTATGATGATGTCGAGTTGGAATTTGA
CGATGAGGCCCTTCAAGAGATTGCCAACAAGGCCATCGAACGGAAGACTGGGGCGCGTGGTCTTCGTTCGATTATTGAAG
AAACCATGTTGGACGTTATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACAAAAGAAGCTGTCGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment