Detailed information NTG0419902

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HYC88_RS20250
• Genome accession: NZ_CP061072
• Coordinates: 4714198..4715322 (-)
• Length: 374 a.a.
• NCBI ID: WP_003968311.1
• Uniprot ID: B1VSK3
• Organism: Streptomyces sp. CB00271
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4709198..4720322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HYC88_RS20225 (HYC88_20225)	cseB	4709512..4710225 (-)	714	WP_073806222.1	two-component system response regulator CseB	-
HYC88_RS20230 (HYC88_20230)	-	4710290..4711003 (-)	714	WP_073806221.1	hypothetical protein	-
HYC88_RS20235 (HYC88_20235)	-	4711165..4711836 (-)	672	WP_073806220.1	SigE family RNA polymerase sigma factor	-
HYC88_RS20240 (HYC88_20240)	-	4712055..4712960 (-)	906	WP_047177250.1	A/G-specific adenine glycosylase	-
HYC88_RS20245 (HYC88_20245)	-	4713264..4713998 (+)	735	WP_073806219.1	hypothetical protein	-
HYC88_RS20250 (HYC88_20250)	disA	4714198..4715322 (-)	1125	WP_003968311.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HYC88_RS20255 (HYC88_20255)	radA/sms	4715402..4716823 (-)	1422	WP_073806218.1	DNA repair protein RadA	Machinery gene
HYC88_RS20260 (HYC88_20260)	-	4716980..4718917 (+)	1938	WP_073806217.1	BACON domain-containing protein	-
HYC88_RS20265 (HYC88_20265)	-	4718935..4719801 (-)	867	WP_073806216.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40408.36 Da
• Isoelectric Point: 5.0230

>NTDB_id=419902 HYC88_RS20250 WP_003968311.1 4714198..4715322(-) (disA) [Streptomyces sp. CB00271]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIHTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=419902 HYC88_RS20250 WP_003968311.1 4714198..4715322(-) (disA) [Streptomyces sp. CB00271]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCCCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAATACCGGTGGGCTGATCGTGC
TGGGCATGGACAAGACCGTCGAGTCGATGTGCACCGGCGGATTCGTGCTGGACGTGGAGTTCACGGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGGGCGCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCCTCGATCCACACGGAGGAGACGGGCACCCGTCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCC
ATCCTGTCCCGGGCCAATCAGGCGCTCGCCACGCTGGAGCGGTACAAACTGCGCCTCGACGAGGTGGCGGGCACGCTGTC
CGCCCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CCACGGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGACGCCTGCTCTCCCTCCAGCTGGACGAGCTGATCGCG
GGTGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGACTACGTCCCCGAGCCGACGGCGAAGCGGTCGCGCACGGTGGCCGA
GGCGCTGACCGAGCTGGACGCGCTGAGCCATACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCGGAGACGCTGGACTCGGCGGTGTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTGGCGGCGAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAAGCGCGGGCGCGCAGCGTGCGGGAGGGGCTTTCGCGGTTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: B1VSK3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436