Detailed information NTG0419586

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: IBC03_RS06875
• Genome accession: NZ_CP061025
• Coordinates: 1329076..1329720 (-)
• Length: 214 a.a.
• NCBI ID: WP_002951384.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 13496
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1324076..1334720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC03_RS06850 (IBC03_06865)	-	1326304..1327302 (-)	999	WP_011226284.1	NAD(P)/FAD-dependent oxidoreductase	-
IBC03_RS06855 (IBC03_06870)	trmD	1327304..1328023 (-)	720	WP_002951382.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
IBC03_RS06860 (IBC03_06875)	rimM	1328013..1328531 (-)	519	WP_011226286.1	ribosome maturation factor RimM	-
IBC03_RS06875 (IBC03_06890)	vraR	1329076..1329720 (-)	645	WP_002951384.1	response regulator transcription factor	Regulator
IBC03_RS06880 (IBC03_06895)	-	1329710..1330720 (-)	1011	WP_011226288.1	sensor histidine kinase	-
IBC03_RS06885 (IBC03_06900)	liaF	1330717..1331415 (-)	699	WP_011226289.1	cell wall-active antibiotics response protein LiaF	-
IBC03_RS10265	-	1331670..1331837 (-)	168	WP_014608530.1	potassium channel family protein	-
IBC03_RS06895 (IBC03_06910)	stkP/pknB	1332474..1334345 (-)	1872	WP_014621795.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24048.39 Da
• Isoelectric Point: 4.5864

>NTDB_id=419586 IBC03_RS06875 WP_002951384.1 1329076..1329720(-) (vraR) [Streptococcus thermophilus strain 13496]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide

• Length: 645 bp

>NTDB_id=419586 IBC03_RS06875 WP_002951384.1 1329076..1329720(-) (vraR) [Streptococcus thermophilus strain 13496]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGATATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-118)

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	50.485	96.262	0.486
degU	Bacillus subtilis subsp. subtilis str. 168	36.161	100	0.379