Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   IBB97_RS09240 Genome accession   NZ_CP061021
Coordinates   1781537..1781830 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain 24739     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1776537..1786830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBB97_RS09210 (IBB97_09225) - 1777064..1777261 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  IBB97_RS09215 (IBB97_09230) - 1777510..1778703 (-) 1194 WP_014608740.1 acetate kinase -
  IBB97_RS09220 (IBB97_09235) comGH 1778759..1779715 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  IBB97_RS09225 (IBB97_09240) comGG 1779760..1780080 (-) 321 WP_278249177.1 competence type IV pilus minor pilin ComGG Machinery gene
  IBB97_RS09230 (IBB97_09245) - 1780101..1781036 (-) 936 WP_138496752.1 IS30 family transposase -
  IBB97_RS09235 (IBB97_09250) comGF 1781119..1781553 (-) 435 WP_138496599.1 competence type IV pilus minor pilin ComGF Machinery gene
  IBB97_RS09240 (IBB97_09255) comGE 1781537..1781830 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  IBB97_RS09245 (IBB97_09260) comGD 1781802..1782230 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  IBB97_RS09250 (IBB97_09265) comGC 1782190..1782516 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  IBB97_RS09255 (IBB97_09270) comGB 1782513..1783613 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  IBB97_RS09260 (IBB97_09275) comGA/cglA/cilD 1783495..1784436 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  IBB97_RS09265 (IBB97_09280) - 1784517..1784879 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=419214 IBB97_RS09240 WP_011226625.1 1781537..1781830(-) (comGE) [Streptococcus thermophilus strain 24739]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=419214 IBB97_RS09240 WP_011226625.1 1781537..1781830(-) (comGE) [Streptococcus thermophilus strain 24739]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361