Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   IBB97_RS09220 Genome accession   NZ_CP061021
Coordinates   1778759..1779715 (-) Length   318 a.a.
NCBI ID   WP_011226622.1    Uniprot ID   Q5M2G5
Organism   Streptococcus thermophilus strain 24739     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1773759..1784715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBB97_RS09190 (IBB97_09205) proC 1774320..1775090 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -
  IBB97_RS09195 (IBB97_09210) - 1775120..1775782 (-) 663 WP_138496727.1 type II CAAX endopeptidase family protein -
  IBB97_RS09200 (IBB97_09215) - 1775879..1776322 (-) 444 WP_011681680.1 hypothetical protein -
  IBB97_RS10605 - 1776396..1776734 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  IBB97_RS09210 (IBB97_09225) - 1777064..1777261 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  IBB97_RS09215 (IBB97_09230) - 1777510..1778703 (-) 1194 WP_014608740.1 acetate kinase -
  IBB97_RS09220 (IBB97_09235) comGH 1778759..1779715 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  IBB97_RS09225 (IBB97_09240) comGG 1779760..1780080 (-) 321 WP_278249177.1 competence type IV pilus minor pilin ComGG Machinery gene
  IBB97_RS09230 (IBB97_09245) - 1780101..1781036 (-) 936 WP_138496752.1 IS30 family transposase -
  IBB97_RS09235 (IBB97_09250) comGF 1781119..1781553 (-) 435 WP_138496599.1 competence type IV pilus minor pilin ComGF Machinery gene
  IBB97_RS09240 (IBB97_09255) comGE 1781537..1781830 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  IBB97_RS09245 (IBB97_09260) comGD 1781802..1782230 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  IBB97_RS09250 (IBB97_09265) comGC 1782190..1782516 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  IBB97_RS09255 (IBB97_09270) comGB 1782513..1783613 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  IBB97_RS09260 (IBB97_09275) comGA/cglA/cilD 1783495..1784436 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35857.00 Da        Isoelectric Point: 4.7123

>NTDB_id=419211 IBB97_RS09220 WP_011226622.1 1778759..1779715(-) (comGH) [Streptococcus thermophilus strain 24739]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRILKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=419211 IBB97_RS09220 WP_011226622.1 1778759..1779715(-) (comGH) [Streptococcus thermophilus strain 24739]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA
GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGATCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

68.889

99.057

0.682
  comGH Streptococcus mutans UA140

68.889

99.057

0.682

Multiple sequence alignment