Detailed information NTG0419077

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: IBC04_RS06745
• Genome accession: NZ_CP061020
• Coordinates: 1302809..1303453 (-)
• Length: 214 a.a.
• NCBI ID: WP_002951384.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 24740
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1297809..1308453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC04_RS06720 (IBC04_06740)	-	1300036..1301034 (-)	999	WP_011226284.1	NAD(P)/FAD-dependent oxidoreductase	-
IBC04_RS06725 (IBC04_06745)	trmD	1301036..1301755 (-)	720	WP_002951382.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
IBC04_RS06730 (IBC04_06750)	rimM	1301745..1302263 (-)	519	WP_011226286.1	ribosome maturation factor RimM	-
IBC04_RS06745 (IBC04_06765)	vraR	1302809..1303453 (-)	645	WP_002951384.1	response regulator transcription factor	Regulator
IBC04_RS06750 (IBC04_06770)	-	1303443..1304453 (-)	1011	WP_011226288.1	sensor histidine kinase	-
IBC04_RS06755 (IBC04_06775)	liaF	1304450..1305148 (-)	699	WP_011226289.1	cell wall-active antibiotics response protein LiaF	-
IBC04_RS10250	-	1305403..1305570 (-)	168	WP_014608530.1	potassium channel family protein	-
IBC04_RS06765 (IBC04_06785)	stkP/pknB	1306207..1308078 (-)	1872	WP_014621795.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24048.39 Da
• Isoelectric Point: 4.5864

>NTDB_id=419077 IBC04_RS06745 WP_002951384.1 1302809..1303453(-) (vraR) [Streptococcus thermophilus strain 24740]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide

• Length: 645 bp

>NTDB_id=419077 IBC04_RS06745 WP_002951384.1 1302809..1303453(-) (vraR) [Streptococcus thermophilus strain 24740]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGATATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-118)

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	50.485	96.262	0.486
degU	Bacillus subtilis subsp. subtilis str. 168	36.161	100	0.379