Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   IBC08_RS06690 Genome accession   NZ_CP061019
Coordinates   1293421..1294065 (-) Length   214 a.a.
NCBI ID   WP_207559816.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 24853     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1288421..1299065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBC08_RS06665 (IBC08_06645) - 1290524..1291522 (-) 999 WP_207559814.1 NAD(P)/FAD-dependent oxidoreductase -
  IBC08_RS06670 (IBC08_06650) trmD 1291524..1292243 (-) 720 WP_207559815.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  IBC08_RS06675 (IBC08_06655) rimM 1292233..1292751 (-) 519 WP_011681402.1 ribosome maturation factor RimM -
  IBC08_RS06690 (IBC08_06670) vraR 1293421..1294065 (-) 645 WP_207559816.1 response regulator transcription factor Regulator
  IBC08_RS06695 (IBC08_06675) - 1294055..1295065 (-) 1011 WP_180479473.1 sensor histidine kinase -
  IBC08_RS06700 (IBC08_06680) liaF 1295062..1295760 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  IBC08_RS10055 - 1296015..1296182 (-) 168 WP_014727613.1 potassium channel family protein -
  IBC08_RS06710 (IBC08_06690) stkP/pknB 1296817..1298688 (-) 1872 WP_014727614.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24074.42 Da        Isoelectric Point: 4.5222

>NTDB_id=418976 IBC08_RS06690 WP_207559816.1 1293421..1294065(-) (vraR) [Streptococcus thermophilus strain 24853]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSYPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=418976 IBC08_RS06690 WP_207559816.1 1293421..1294065(-) (vraR) [Streptococcus thermophilus strain 24853]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTTACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.818

100

0.379