Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H9192_RS09480 Genome accession   NZ_CP060974
Coordinates   1972225..1972881 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967225..1977881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H9192_RS09450 (H9192_09375) dcyD 1968105..1969091 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  H9192_RS09455 (H9192_09380) tcyL 1969106..1969774 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  H9192_RS09460 (H9192_09385) tcyN 1969771..1970523 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  H9192_RS09465 (H9192_09390) sdiA 1970753..1971475 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  H9192_RS09470 (H9192_09395) yecF 1971542..1971766 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  H9192_RS09475 (H9192_09400) yecU 1971753..1971929 (-) 177 WP_000590344.1 protein YecU -
  H9192_RS24940 - 1971967..1972083 (-) 117 WP_001302039.1 hypothetical protein -
  H9192_RS09480 (H9192_09405) letA 1972225..1972881 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  H9192_RS09485 (H9192_09410) uvrC 1972878..1974710 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  H9192_RS09490 (H9192_09415) pgsA 1974767..1975315 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  H9192_RS09510 (H9192_09435) yecA 1975964..1976629 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=418598 H9192_RS09480 WP_000611328.1 1972225..1972881(+) (letA) [Escherichia coli strain EC4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=418598 H9192_RS09480 WP_000611328.1 1972225..1972881(+) (letA) [Escherichia coli strain EC4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTAACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482