Detailed information NTG0418462

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GWG03_RS05200
• Genome accession: NZ_CP047924
• Coordinates: 1050832..1051818 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain SR130
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1045832..1056818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GWG03_RS05175 (GWG03_05190)	-	1046092..1046439 (-)	348	WP_001242103.1	hypothetical protein	-
GWG03_RS05180 (GWG03_05195)	-	1046625..1047218 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
GWG03_RS05185 (GWG03_05200)	-	1047322..1047687 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
GWG03_RS05190 (GWG03_05205)	yjbH	1047710..1048516 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
GWG03_RS05195 (GWG03_05210)	pepF	1048976..1050784 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
GWG03_RS05200 (GWG03_05215)	coiA	1050832..1051818 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
GWG03_RS05205 (GWG03_05220)	mecA	1051939..1052658 (-)	720	WP_001217728.1	adaptor protein MecA	-
GWG03_RS05210 (GWG03_05225)	spxA	1053029..1053424 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
GWG03_RS05215 (GWG03_05230)	trpS	1053718..1054707 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
GWG03_RS05220 (GWG03_05235)	opp4C	1054749..1055630 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
GWG03_RS05225 (GWG03_05240)	opp4B	1055642..1056604 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418462 GWG03_RS05200 WP_000959282.1 1050832..1051818(-) (coiA) [Staphylococcus aureus strain SR130]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418462 GWG03_RS05200 WP_000959282.1 1050832..1051818(-) (coiA) [Staphylococcus aureus strain SR130]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976