Detailed information NTG0418417

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GWG04_RS05615
• Genome accession: NZ_CP047922
• Coordinates: 1111600..1112586 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain SR231
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1106600..1117586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GWG04_RS05590 (GWG04_05595)	-	1106860..1107207 (-)	348	WP_001242103.1	hypothetical protein	-
GWG04_RS05595 (GWG04_05600)	-	1107393..1107986 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
GWG04_RS05600 (GWG04_05605)	-	1108090..1108455 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
GWG04_RS05605 (GWG04_05610)	yjbH	1108478..1109284 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
GWG04_RS05610 (GWG04_05615)	pepF	1109744..1111552 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
GWG04_RS05615 (GWG04_05620)	coiA	1111600..1112586 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
GWG04_RS05620 (GWG04_05625)	mecA	1112707..1113426 (-)	720	WP_001217728.1	adaptor protein MecA	-
GWG04_RS05625 (GWG04_05630)	spxA	1113797..1114192 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
GWG04_RS05630 (GWG04_05635)	trpS	1114486..1115475 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
GWG04_RS05635 (GWG04_05640)	opp4C	1115517..1116398 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
GWG04_RS05640 (GWG04_05645)	opp4B	1116410..1117372 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418417 GWG04_RS05615 WP_000959282.1 1111600..1112586(-) (coiA) [Staphylococcus aureus strain SR231]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418417 GWG04_RS05615 WP_000959282.1 1111600..1112586(-) (coiA) [Staphylococcus aureus strain SR231]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976