Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   GWG04_RS05140 Genome accession   NZ_CP047922
Coordinates   1035322..1035891 (+) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain SR231     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1030322..1040891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWG04_RS05105 (GWG04_05125) - 1031536..1031808 (-) 273 WP_001797239.1 lactococcin 972 family bacteriocin -
  GWG04_RS05110 (GWG04_05130) - 1031818..1031919 (-) 102 WP_031763719.1 hypothetical protein -
  GWG04_RS14850 - 1032458..1032535 (-) 78 WP_099112139.1 putative holin-like toxin -
  GWG04_RS05120 (GWG04_05140) - 1032835..1033437 (-) 603 WP_001033865.1 CPBP family glutamic-type intramembrane protease -
  GWG04_RS05125 (GWG04_05145) - 1033452..1033628 (-) 177 WP_000214898.1 YkvS family protein -
  GWG04_RS05130 (GWG04_05150) - 1033827..1034813 (+) 987 WP_000668818.1 lipoate--protein ligase -
  GWG04_RS05135 (GWG04_05155) - 1034894..1035112 (-) 219 WP_000876826.1 IDEAL domain-containing protein -
  GWG04_RS05140 (GWG04_05160) comK/comK1 1035322..1035891 (+) 570 WP_000287265.1 competence protein ComK Regulator
  GWG04_RS05155 (GWG04_05175) - 1036378..1037889 (-) 1512 WP_000414165.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  GWG04_RS05160 (GWG04_05180) - 1038028..1039386 (-) 1359 WP_103147894.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=418416 GWG04_RS05140 WP_000287265.1 1035322..1035891(+) (comK/comK1) [Staphylococcus aureus strain SR231]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=418416 GWG04_RS05140 WP_000287265.1 1035322..1035891(+) (comK/comK1) [Staphylococcus aureus strain SR231]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCTATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1

Multiple sequence alignment