Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GV831_RS00625 Genome accession   NZ_CP047891
Coordinates   125873..126574 (+) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis subsp. lactis strain WHH2311     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 120873..131574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GV831_RS00610 (GV831_00595) - 123267..124175 (+) 909 WP_003130548.1 diacylglycerol kinase family protein -
  GV831_RS00615 (GV831_00600) - 124323..125009 (+) 687 WP_004255158.1 amino acid ABC transporter permease -
  GV831_RS00620 (GV831_00605) - 125009..125743 (+) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  GV831_RS00625 (GV831_00610) mecA 125873..126574 (+) 702 WP_004255173.1 adaptor protein MecA Regulator
  GV831_RS00630 (GV831_00615) - 126577..127908 (+) 1332 WP_004255177.1 MraY family glycosyltransferase -
  GV831_RS00635 (GV831_00620) sufC 128083..128853 (+) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  GV831_RS00640 (GV831_00625) sufD 128988..130247 (+) 1260 WP_373419298.1 Fe-S cluster assembly protein SufD -
  GV831_RS00645 (GV831_00630) - 130247..131464 (+) 1218 WP_004255189.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=418321 GV831_RS00625 WP_004255173.1 125873..126574(+) (mecA) [Lactococcus lactis subsp. lactis strain WHH2311]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=418321 GV831_RS00625 WP_004255173.1 125873..126574(+) (mecA) [Lactococcus lactis subsp. lactis strain WHH2311]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97

Multiple sequence alignment