Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   M594_RS02940 Genome accession   NZ_CP047883
Coordinates   569316..570548 (+) Length   410 a.a.
NCBI ID   WP_012972566.1    Uniprot ID   A0A387B487
Organism   Streptococcus mitis strain S022-V3-A4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 564316..575548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS02905 (M594_02930) galE 565012..566031 (+) 1020 WP_173875910.1 UDP-glucose 4-epimerase GalE -
  M594_RS02910 (M594_02935) - 566015..566998 (+) 984 WP_254597199.1 glycosyltransferase family 2 protein -
  M594_RS02915 (M594_02940) - 567056..567253 (-) 198 WP_173875911.1 ferredoxin -
  M594_RS02920 (M594_02945) - 567299..567799 (+) 501 WP_061590353.1 SAG1386/EF1546 family surface-associated protein -
  M594_RS02925 (M594_02950) cmk 567809..568483 (+) 675 WP_173875912.1 (d)CMP kinase -
  M594_RS02930 (M594_02955) - 568603..569109 (+) 507 WP_173875913.1 dihydrofolate reductase -
  M594_RS02935 (M594_02960) - 569109..569279 (+) 171 WP_112445491.1 hypothetical protein -
  M594_RS02940 (M594_02965) clpX 569316..570548 (+) 1233 WP_012972566.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  M594_RS02945 (M594_02970) yihA 570557..571144 (+) 588 WP_000422604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  M594_RS02950 (M594_02975) - 571155..571535 (+) 381 WP_001140420.1 RidA family protein -
  M594_RS02955 (M594_02980) rapZ 571587..572477 (+) 891 WP_084925753.1 RNase adapter RapZ -
  M594_RS02960 (M594_02985) - 572474..573451 (+) 978 WP_060627753.1 YvcK family protein -
  M594_RS02965 (M594_02990) whiA 573448..574359 (+) 912 WP_173875914.1 DNA-binding protein WhiA -
  M594_RS02970 (M594_02995) - 574394..575362 (-) 969 WP_173875915.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45681.16 Da        Isoelectric Point: 4.4240

>NTDB_id=418248 M594_RS02940 WP_012972566.1 569316..570548(+) (clpX) [Streptococcus mitis strain S022-V3-A4]
MPTNRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=418248 M594_RS02940 WP_012972566.1 569316..570548(+) (clpX) [Streptococcus mitis strain S022-V3-A4]
ATGCCTACAAATAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCAGGTAACAACGCCTTTATCTGTAATGAATGTGTGGAGTTAGCCCAGGAGATCATTCGGGAGGAGTTGGCTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATCGAACTCCTCCACATCTTGAATCACTACGTAATCGGTCAAGATCGT
GCCAAACGTGCCTTGGCAGTAGCTGTATACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAATCAAATATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCGATCGCAGATGCGACAGCTCTTACTGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCCTACAGGCTGCTGACTTTAACATCGAGCGTGCAGAGCGTGGGATTATCTATGTGGATGAAATTGA
CAAGATTGCTAAGAAAAGCGAGAACGTGTCTATCACACGTGATGTTTCTGGTGAAGGTGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACCGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAGCATCCACAACAAGAGATGATTCAAGTGGACACT
AAAAATATCCTCTTCATTGTGGGTGGTGCCTTTGATGGCATTGAAGAAATCGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAATAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATTGCAGAAGATATTCAAAAAT
TTGGTATTATCCCAGAGTTGATTGGACGTTTGCCTGTCTTTGCAGCTCTTGAGCAATTGACGGTTGATGACTTGGTTCGC
ATCTTGAAAGAACCAAGAAATGCCTTGGTCAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCTCTTCAAGAGATTGCCAATAAAGCCATCGAACGTAAAACGGGTGCGCGTGGTCTTCGCTCGATCATCGAAG
AAACCATGCTAGACGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAGCTGTCGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B487

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.073

100

0.871
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment