Detailed information NTG0418155

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S59_RS05560
• Genome accession: NZ_CP047867
• Coordinates: 1101154..1102140 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_419
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1096154..1107140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S59_RS05535 (E3S59_05535)	-	1096414..1096761 (-)	348	WP_001242103.1	hypothetical protein	-
E3S59_RS05540 (E3S59_05540)	-	1096947..1097540 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S59_RS05545 (E3S59_05545)	-	1097644..1098009 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S59_RS05550 (E3S59_05550)	yjbH	1098032..1098838 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S59_RS05555 (E3S59_05555)	pepF	1099298..1101106 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S59_RS05560 (E3S59_05560)	coiA	1101154..1102140 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S59_RS05565 (E3S59_05565)	mecA	1102261..1102980 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S59_RS05570 (E3S59_05570)	spxA	1103351..1103746 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S59_RS05575 (E3S59_05575)	trpS	1104040..1105029 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S59_RS05580 (E3S59_05580)	opp4C	1105071..1105952 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S59_RS05585 (E3S59_05585)	opp4B	1105964..1106926 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418155 E3S59_RS05560 WP_000959282.1 1101154..1102140(-) (coiA) [Staphylococcus aureus strain UP_419]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418155 E3S59_RS05560 WP_000959282.1 1101154..1102140(-) (coiA) [Staphylococcus aureus strain UP_419]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976