Detailed information NTG0418111

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S61_RS05570
• Genome accession: NZ_CP047865
• Coordinates: 1102090..1103076 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_844
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1097090..1108076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S61_RS05545 (E3S61_05545)	-	1097350..1097697 (-)	348	WP_001242103.1	hypothetical protein	-
E3S61_RS05550 (E3S61_05550)	-	1097883..1098476 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S61_RS05555 (E3S61_05555)	-	1098580..1098945 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S61_RS05560 (E3S61_05560)	yjbH	1098968..1099774 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S61_RS05565 (E3S61_05565)	pepF	1100234..1102042 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S61_RS05570 (E3S61_05570)	coiA	1102090..1103076 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S61_RS05575 (E3S61_05575)	mecA	1103197..1103916 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S61_RS05580 (E3S61_05580)	spxA	1104287..1104682 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S61_RS05585 (E3S61_05585)	trpS	1104976..1105965 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S61_RS05590 (E3S61_05590)	opp4C	1106007..1106888 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S61_RS05595 (E3S61_05595)	opp4B	1106900..1107862 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418111 E3S61_RS05570 WP_000959282.1 1102090..1103076(-) (coiA) [Staphylococcus aureus strain UP_844]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418111 E3S61_RS05570 WP_000959282.1 1102090..1103076(-) (coiA) [Staphylococcus aureus strain UP_844]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976