Detailed information NTG0418067

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E3S63_RS05250
• Genome accession: NZ_CP047863
• Coordinates: 1056395..1057381 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain UP_1106
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1051395..1062381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S63_RS05225 (E3S63_05225)	-	1051655..1052002 (-)	348	WP_001242103.1	hypothetical protein	-
E3S63_RS05230 (E3S63_05230)	-	1052188..1052781 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
E3S63_RS05235 (E3S63_05235)	-	1052885..1053250 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
E3S63_RS05240 (E3S63_05240)	yjbH	1053273..1054079 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
E3S63_RS05245 (E3S63_05245)	pepF	1054539..1056347 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
E3S63_RS05250 (E3S63_05250)	coiA	1056395..1057381 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
E3S63_RS05255 (E3S63_05255)	mecA	1057502..1058221 (-)	720	WP_001217728.1	adaptor protein MecA	-
E3S63_RS05260 (E3S63_05260)	spxA	1058592..1058987 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
E3S63_RS05265 (E3S63_05265)	trpS	1059281..1060270 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
E3S63_RS05270 (E3S63_05270)	opp4C	1060312..1061193 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
E3S63_RS05275 (E3S63_05275)	opp4B	1061205..1062167 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=418067 E3S63_RS05250 WP_000959282.1 1056395..1057381(-) (coiA) [Staphylococcus aureus strain UP_1106]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=418067 E3S63_RS05250 WP_000959282.1 1056395..1057381(-) (coiA) [Staphylococcus aureus strain UP_1106]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976